[HTML][HTML] Recent insights into the role of PPARs in disease
N Wagner, KD Wagner - Cells, 2023 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that play
important roles in cell proliferation, differentiation, metabolism, and cancer [1–5]. They were …
important roles in cell proliferation, differentiation, metabolism, and cancer [1–5]. They were …
[HTML][HTML] Exploring Rosiglitazone's Potential to Treat Alzheimer's Disease through the Modulation of Brain-Derived Neurotrophic Factor
ML Nelson, JA Pfeifer, JP Hickey, AE Collins… - Biology, 2023 - mdpi.com
Simple Summary This review focuses on rosiglitazone, a medication used to treat diabetes.
Rosiglitazone lowers blood sugar levels by helping the body use insulin more efficiently …
Rosiglitazone lowers blood sugar levels by helping the body use insulin more efficiently …
Peroxisome Proliferator-Activated Receptor agonists and antagonists: an updated patent review (2020–2023)
B De Filippis, A Granese… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction The search for novel compounds targeting Peroxisome Proliferator-Activated
Receptors (PPARs) is currently ongoing, starting from the previous successfully identification …
Receptors (PPARs) is currently ongoing, starting from the previous successfully identification …
[HTML][HTML] Gastrodin ameliorates neuroinflammation in Alzheimer's disease mice by inhibiting NF-κB signaling activation via PPARγ stimulation
H Yin, R Liu, L Bie - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Aim: We investigated the effects and targets of gastrodin (GAS) for improving cognitive ability
in Alzheimer's disease (AD). Methods: The targets and mechanisms of GAS were analyzed …
in Alzheimer's disease (AD). Methods: The targets and mechanisms of GAS were analyzed …
[HTML][HTML] Flavonols as a Potential Pharmacological Intervention for Alleviating Cognitive Decline in Diabetes: Evidence from Preclinical Studies
Diabetes mellitus is a complex metabolic disease associated with reduced synaptic
plasticity, atrophy of the hippocampus, and cognitive decline. Cognitive impairment results …
plasticity, atrophy of the hippocampus, and cognitive decline. Cognitive impairment results …
[HTML][HTML] Dual PPAR delta/gamma agonists offer therapeutic potential for Alzheimer's disease
The increasing incidence of Alzheimer's disease (AD) in the aging population, indicates the
critical need for the development of novel targeted molecular therapies for ameliorating AD …
critical need for the development of novel targeted molecular therapies for ameliorating AD …
双重PPARδ/γ 激动剂为阿尔茨海默病提供治疗潜力
I Steinke, M Singh, R Amin - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
The increasing incidence of Alzheimer's disease (AD) in the aging population, indicates the
critical need for the development of novel targeted molecular therapies for ameliorating AD …
critical need for the development of novel targeted molecular therapies for ameliorating AD …