Authentication of Three Source Spices of Arnebiae Radix Using DNA Barcoding and HPLC

H Xu, P Li, G Ren, Y Wang, D Jiang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Arnebia decumbens (Vent.) Coss. et Kralik, A. euchroma (Royle) Johnst and A. guttata
Bunge, three commonly used traditional Chinese medicinal plants have been widely used …

Constitutive Androstane Receptor Agonist, TCPOBOP: Maternal Exposure Impairs the Growth and Development of Female Offspring in Mice

S Pan, Y Guo, W Yu, J Zhang, X Qiao, L Li… - International Journal of …, 2023 - mdpi.com
Environmental chemicals, which are known to impact offspring health, have become a public
concern. Constitutive activated receptor (CAR) is activated by various environmental …

Shikonin-induced apoptosis of colon cancer cells is reduced by peroxiredoxin V expression

N Chandimali, HN Sun, LZ Kong, X Zhen… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Colon cancer is the second most common deadliest malignancy in the
world and better understanding of its underlying mechanisms is needed to improve clinical …

Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in …

Y Lei, X Lei, A Zhu, S Xie, T Zhang, C Wang, A Song… - Molecules, 2023 - mdpi.com
Acetaminophen (APAP)-induced liver injury is a common hepatic disease resulting from
drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of …

Dibenzocyclooctadiene lignans from Kadsura coccinea alleviate APAP-induced hepatotoxicity via oxidative stress inhibition and activating the Nrf2 pathway in vitro

Y Yang, Y Jian, S Cheng, Y Jia, Y Liu, H Yu, L Cao… - Bioorganic …, 2021 - Elsevier
Phytochemical investigation on the roots of Kadsura coccinea led to the isolation five
previously unknown dibenzocyclooctadiene lignans, named heilaohusuins AE (1–5). Their …

Effect of fine particulate matter exposure on liver enzymes: a systematic review and meta-analysis

L Pan, J Sui, Y Xu, Q Zhao, Y Cai, G Sun… - International Journal of …, 2023 - mdpi.com
Although previous studies have presented that fine particulate matter (PM2. 5) regulates
liver enzyme levels in the development of liver diseases, the evidence regarding the …

Untargeted lipidomics-based study reveals the treatment mechanism of Qingxue Bawei tablets on atherosclerotic in ApoE−/− mice

Z Du, X Zhao, L Sun, B Chi, Z Ma, Z Tian… - Journal of Chromatography …, 2023 - Elsevier
Qingxue Bawei (QXBW) tablets, a Mongolian medicine prescription, have proved to possess
good lipid-lowering and antihypertensive effects in previous studies. However, the …

Concurrent administration of farnesol protects acetaminophen‐induced acute hepatic necrosis in mice

R Gayatri Devi, D Ezhilarasan - Journal of Biochemical and …, 2023 - Wiley Online Library
Acetaminophen (APAP) is known to cause acute liver injury and acute liver failure in
Western countries. This study investigates the protective role of farnesol (FAR)(C15H26O), a …

Glycyrrhizic acid mitigates tripterygium-glycoside-tablet-induced acute liver injury via PKM2 regulated oxidative stress

Q Wang, Y Huang, Y Li, L Zhang, H Tang, J Zhang… - Metabolites, 2022 - mdpi.com
Tripterygium glycoside tablet (TGT), as a common clinical drug, can easily cause liver
damage due to the narrow therapeutic window. Glycyrrhizic acid (GA) has a …

Shikonin attenuates H2O2‑induced oxidative injury in HT29 cells via antioxidant activities and the inhibition of mitochondrial pathway‑mediated apoptosis

Y Zhong, A Qi, L Liu, Q Huang… - Experimental and …, 2021 - spandidos-publications.com
Shikonin, a natural naphthoquinone extracted from the roots of Lithospermumery throrhizon,
possesses multiple pharmacological properties, including antioxidant, anti‑inflammatory and …