The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

The development of effective vaccines to combat infectious diseases is a complex multi-year
and multi-stakeholder process. To accelerate the development of vaccines for coronavirus …

Background At interim analysis in a phase 3, observer-blinded, placebo-controlled clinical
trial, the mRNA-1273 vaccine showed 94.1% efficacy in preventing coronavirus disease …

Importance Persons with immune dysfunction have a higher risk for severe COVID-19
outcomes. However, these patients were largely excluded from SARS-CoV-2 vaccine …

The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). To halt the pandemic, multiple SARS-CoV-2 …

Background Solid organ transplant (SOT) recipients are at increased risks of morbidity and
mortality associated with COVID-19. Objectives This study aimed to evaluate the …

Background & Aims Patients with immune-mediated inflammatory diseases (IMIDs) have an
increased risk of coronavirus disease 2019 (COVID-19), primarily attributed to the use of …

Background Immunocompromised (IC) patients are at higher risk of severe SARS-CoV-2
infection, morbidity, and mortality compared to the general population. They should be …

Background Cancer patients particularly those with hematological malignancies are at
higher risk of affecting by severe coronavirus disease 2019 (COVID-19). Due to the …