The past two decades have contributed a large body of preclinical work that has assisted in
our understanding of the underlying pathophysiological mechanisms that cause chronic …

This umbrella review aimed to determine the various drugs used to treat trigeminal neuralgia
(TN) and to evaluate their efficacies as well as side effects by surveying previously …

Background Peripheral neuropathic pain (PNP) associated with allodynia poses a
significant clinical challenge. The efficacy of Δ9‐tetrahydrocannabinol/cannabidiol …

Advances in supportive care have increased the likelihood that previously less common
adverse effects of chemotherapy will be more evident. The incidence of chemotherapy …

Background Between 1992 and 2001 the UK general practice incidence of post-herpetic
neuralgia and trigeminal neuralgia declined, whilst the incidence of painful diabetic …

Peripheral neuropathic pain (PNP) poses a significant clinical challenge. The long-term
efficacy of delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD) oromucosal spray was …

Background: Trigeminal neuralgia is a syndrome of paroxysmal excruciating, lancinating
unilateral facial pain. Review Summary: There are several clinical features that are …

Refractory neuropathic pain can be devastating to a patient's quality of life. Ideally, the
primary goal of therapy would be to prevent the pain, yet even the most appropriate …

Background Thirty percent to ninety percent of cancer patients suffer from pain, including
neuropathic pain (NP), which results in great burden for cancer patients. Thus, it was of great …

Tricyclic antidepressants (TCAs), such as desipramine (DMI), are effective at managing
neuropathic pain symptoms but often take several weeks to become effective and also lead …