The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Nanoparticles in drug delivery: From history to therapeutic applications
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches
K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …
therapy, currently, there is no significant progress in the treatment of different types of brain …
Functionalized nanomaterials capable of crossing the blood–brain barrier
The blood–brain barrier (BBB) is a specialized semipermeable structure that highly
regulates exchanges between the central nervous system parenchyma and blood vessels …
regulates exchanges between the central nervous system parenchyma and blood vessels …
Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain
The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …
tightly controls the transport of materials between the blood and the brain. There is an …
Liposomes for the treatment of brain cancer—A review
Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes
are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate …
are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate …
Applications of focused ultrasound for the treatment of glioblastoma: a new frontier
AM Hersh, M Bhimreddy, C Weber-Levine, K Jiang… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …
Nanogels as target drug delivery systems in cancer therapy: A review of the last decade
AA Attama, PO Nnamani, OB Onokala… - Frontiers in …, 2022 - frontiersin.org
Cancer is an important cause of morbidity and mortality worldwide, irrespective of the level
of human development. Globally, it was estimated that there were 19.3 million new cases of …
of human development. Globally, it was estimated that there were 19.3 million new cases of …
Exosomes: promising delivery tools for overcoming blood-brain barrier and glioblastoma therapy
Gliomas make up virtually 80% of all lethal primary brain tumors and are categorized based
on their cell of origin. Glioblastoma is an astrocytic tumor that has an inferior prognosis …
on their cell of origin. Glioblastoma is an astrocytic tumor that has an inferior prognosis …
New advances in biomedical application of polymeric micelles
A Figueiras, C Domingues, I Jarak, AI Santos, A Parra… - Pharmaceutics, 2022 - mdpi.com
In the last decade, nanomedicine has arisen as an emergent area of medicine, which
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …