Neuroprotective potential of limonene and limonene containing natural products

LB Eddin, NK Jha, MFN Meeran, KK Kesari, R Beiram… - Molecules, 2021 - mdpi.com
Limonene is a monoterpene confined to the family of Rutaceae, showing several biological
properties such as antioxidant, anti-inflammatory, anticancer, antinociceptive and …

Impact of natural compounds on neurodegenerative disorders: from preclinical to pharmacotherapeutics

M Sharifi-Rad, C Lankatillake, DA Dias… - Journal of Clinical …, 2020 - mdpi.com
Among the major neurodegenerative disorders (NDDs), Alzheimer's disease (AD) and
Parkinson's disease (PD), are a huge socioeconomic burden. Over many centuries, people …

Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside

F Islam, MH Nafady, MR Islam, S Saha, S Rashid… - Molecular …, 2022 - Springer
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

Natural products attenuate PI3K/Akt/mTOR signaling pathway: A promising strategy in regulating neurodegeneration

S Fakhri, A Iranpanah, MM Gravandi, SZ Moradi… - Phytomedicine, 2021 - Elsevier
Background As common, progressive, and chronic causes of disability and death,
neurodegenerative diseases (NDDs) significantly threaten human health, while no effective …

An insight into novel therapeutic potentials of taxifolin

Y Liu, X Shi, Y Tian, S Zhai, Y Liu, Z Xiong… - Frontiers in …, 2023 - frontiersin.org
Taxifolin is a flavonoid compound, originally isolated from the bark of Douglas fir trees,
which is often found in foods such as onions and olive oil, and is also used in commercial …

Evaluation of biological activity of natural compounds: current trends and methods

C Barba-Ostria, SE Carrera-Pacheco… - Molecules, 2022 - mdpi.com
Natural compounds have diverse structures and are present in different forms of life.
Metabolites such as tannins, anthocyanins, and alkaloids, among others, serve as a defense …

Reactive oxygen species as a link between antioxidant pathways and autophagy

D Li, Z Ding, K Du, X Ye… - Oxidative Medicine and …, 2021 - Wiley Online Library
Reactive oxygen species (ROS) are highly reactive molecules that can oxidize proteins,
lipids, and DNA. Under physiological conditions, ROS are mainly generated in the …

The neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and …

MS Karvandi, F Sheikhzadeh Hesari… - Frontiers in Cellular …, 2023 - frontiersin.org
Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …

Resveratrol derivatives as potential treatments for Alzheimer's and Parkinson's disease

BD Arbo, C André-Miral, RG Nasre-Nasser… - Frontiers in aging …, 2020 - frontiersin.org
Neurodegenerative diseases are characterized by the progressive loss of neurons in
different regions of the nervous system. Alzheimer's disease (AD) and Parkinson's disease …

Natural compounds and autophagy: allies against neurodegeneration

A Stacchiotti, G Corsetti - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Prolonging the healthy life span and limiting neurological illness are imperative goals in
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …