Modulation of the biochemical composition of the tumour microenvironment is a new frontier
of cancer therapy. Several immunosuppressive mechanisms operate in the milieu of most …

Until recently, the nucleic acid content of platelets was considered to be fully determined by
their progenitor megakaryocyte. However, it is now well understood that additional …

Tumor cells initiate platelet activation leading to the secretion of bioactive molecules, which
promote metastasis. Platelet receptors on tumors have not been well-characterized …

Thrombosis is a frequent issue in cancer patients. Tumor-induced platelet activation and
coagulation does not only constitute a significant risk for thrombosis, but also contribute to …

The present work aims to prove the concept of tumor-targeted drug delivery mediated by
platelets. Doxorubicin (DOX) attached to nanodiamonds (ND-DOX) was investigated as the …

Several lines of evidence are consistent with the hypothesis that activated platelets
contribute to colorectal tumorigenesis and metastatization through direct cell–cell …

Contrary to many reports that antiplatelet agents inhibit cancer growth and metastasis, new
solid tumors have been reported in patients receiving long-term antiplatelet therapy. We …

The edible bamboo mushroom Dictyophora indusiata, which is rich in food nutrients and has
medicinal values, has been investigated for nutrition compositional analysis. Then, three …

The perioperative trauma-related platelet recruitment and activation severely affect tumor
recurrence and metastasis. Therefore, efficiently killing residual tumor cells and …

Background In addition to their pivotal roles in coagulation and thrombosis, platelets are
crucial in tumor progression, with plenty of clinical and experimental data demonstrating that …