Hippocampus‐based behavioral, structural, and molecular dynamics across the estrous cycle

D Rocks, M Kundakovic - Journal of neuroendocrinology, 2023 - Wiley Online Library
The activity of neurons in the rodent hippocampus contributes to diverse behaviors, with the
activity of ventral hippocampal neurons affecting behaviors related to anxiety and emotion …

Targeting Nociceptin/Orphanin FQ receptor to rescue cognitive symptoms in a mouse neuroendocrine model of chronic stress

F D'Oliveira da Silva, C Robert, E Lardant… - Molecular …, 2023 - nature.com
Chronic stress causes cognitive deficits, such as impairments in episodic-like hippocampus-
dependent memory. Stress regulates an opioid-related neuropeptide named …

Impairments in the early consolidation of spatial memories via group II mGluR agonism in the mammillary bodies

MM Milczarek, JC Perry, E Amin, S Haniffa… - Scientific Reports, 2024 - nature.com
Abstract mGluR2 receptors are widely expressed in limbic brain regions associated with
memory, including the hippocampal formation, retrosplenial and frontal cortices, as well as …

[HTML][HTML] Acute stress alters recognition memory and AMPA/NMDA receptor subunits in a sex-dependent manner

SA Torrisi, S Rizzo, S Laudani, A Ieraci, F Drago… - Neurobiology of …, 2023 - Elsevier
Several studies have consistently reported a detrimental effect of chronic stress on
recognition memory. However, the effects of acute stress on this cognitive ability have been …

[HTML][HTML] Cognitive Deficits in human ApoE4 Knock-In Mice: A Systematic Review and Meta-Analysis

MJG avan Heuvelen, MB van der Lei… - Behavioural Brain …, 2024 - Elsevier
Abstract Apolipoprotein-E4 (ApoE4) is an important genetic risk factor for Alzheimer's
disease. The development of targeted-replacement human ApoE knock-in mice facilitates …

Differentiated somatic gene expression is triggered in the dorsal hippocampus and the anterior retrosplenial cortex by hippocampal synaptic plasticity prompted by …

TH Hoang, D Manahan-Vaughan - Brain Structure and Function, 2024 - Springer
Hippocampal afferent inputs, terminating on proximal and distal subfields of the cornus
ammonis (CA), enable the functional discrimination of 'what'(item identity) and …

Electroacupuncture protective effects after cerebral ischemia are mediated through miR-219a inhibition

Y Dai, S Wang, M Yang, P Zhuo, Y Ding, X Li, Y Cao… - Biological Research, 2023 - Springer
Background Electroacupuncture (EA) is a complementary and alternative therapy which has
shown protective effects on vascular cognitive impairment (VCI). However, the underlying …

Passive immunization inhibits tau phosphorylation and improves recognition learning and memory in 3xTg-AD mice

L Li, J Miao, Y Jiang, CL Dai, K Iqbal, F Liu… - Experimental Neurology, 2023 - Elsevier
Tau pathology is essential in the pathogenesis of Alzheimer's disease (AD) and related
tauopathies. Tau immunotherapy aimed at reducing the progression of tau pathology …

Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone

C Delgado-Sallent, T Gener, P Nebot… - Frontiers in Cellular …, 2023 - frontiersin.org
N-methyl D-aspartate receptor (NMDAR) hypofunction is a pathophysiological mechanism
relevant for schizophrenia. Acute administration of the NMDAR antagonist phencyclidine …

[HTML][HTML] The late positive event-related potential component is time locked to the decision in recognition memory tasks

J Sun, AF Osth, D Feuerriegel - Cortex, 2024 - Elsevier
Two event-related potential (ERP) components are commonly observed in recognition
memory tasks: the Frontal Negativity (FN400) and the Late Positive Component (LPC) …