[HTML][HTML] The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

[HTML][HTML] Cornerstone Cellular pathways for metabolic disorders and Diabetes Mellitus: non-coding RNAs, wnt signaling, and AMPK

K Maiese - Cells, 2023 - mdpi.com
Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant …

Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders

K Maiese - Current Neurovascular Research, 2023 - ingentaconnect.com
Microglia account for approximately fifteen percent of the cell population in the brain and
spinal cord. These cells, considered to be family members of glial cells, have an active role …

Mitochondria, mitophagy, Mitoptosis, and programmed cell death: implications from aging to cancer

K Maiese - Current Neurovascular Research, 2024 - ingentaconnect.com
Mitochondria are critical organelles in cells. Mitochondria are found in animal, fungi, and
plant cells and use aerobe respiration to provide energy to the cell through the generation of …

Clinical Depression, the Mechanistic Target of Rapamycin (mTOR), and Forkhead Transcription Factors (FoxOs)

K Maiese - Current Neurovascular Research, 2023 - ingentaconnect.com
Depression is a disorder in the mental health of an individual that leads to a low level of
activity and feelings of despair and hopelessness [1-3]. Depression can lead to the inability …

Cognitive impairment in multiple sclerosis: from phenomenology to neurobiological mechanisms

KA Jellinger - Journal of Neural Transmission, 2024 - Springer
Multiple sclerosis (MS) is an autoimmune-mediated disease of the central nervous system
characterized by inflammation, demyelination and chronic progressive neurodegeneration …

Effects of Dry Needling on Gastrocnemius Muscle Spasticity and Gait in Patients with Multiple Sclerosis: A Pilot Randomized Controlled Trial

O Motamedzadeh, N Nakhostin Ansari… - Medical …, 2024 - liebertpub.com
Objective: Spasticity is a common complication in patients with multiple sclerosis (pwMS).
The present study aimed to evaluate the clinical, biomechanical, and functional effects of dry …

[HTML][HTML] Risk Factors for Cognitive Impairment in Multiple Sclerosis Patients

TG Schreiner, I Mihoc, E Grigore, OD Schreiner - Sclerosis, 2024 - mdpi.com
Cognitive impairment is one of the most significant burdens among the many neurological
complaints in multiple sclerosis patients. Cognitive deficits negatively impact these patients' …