Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In
cancer cells, metabolic pathway activity varies during tumorigenesis and cancer …

During the perinatal period, the brain is particularly sensitive to remodelling by
environmental factors. Adverse early‐life experiences, such as stress exposure or …

Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …

Although the critical role for epigenetic mechanisms in development and cell differentiation
has long been appreciated, recent evidence reveals that these mechanisms are also …

Over the past 25 years, the broad field of epigenetics and, over the past decade in particular,
the emerging field of neuroepigenetics have begun to have tremendous impact in the areas …

Evidence is emerging that several diseases and behavioral pathologies result from defects
in gene function. The best-studied example is cancer, but other diseases such as …

An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …

Limited information is available regarding epigenomic events mediating initiation and
progression of tobacco-induced lung cancers. In this study, we established an in vitro system …

Covering: up to the end of September 2009 The covalent modification of chromatin is an
important control mechanism used by fungi to modulate the transcription of genes involved …

Several lines of evidence point to the early origin of adult onset disease. A key question is:
what are the mechanisms that mediate the effects of the early environment on our health …