Mast cells (MCs) are crucial cells participating in both innate and adaptive immune
processes that play important roles in protecting human health and in the pathophysiology of …

The characteristics of the tumour cells, as well as how tumour cells interact with their
surroundings, affect the prognosis of cancer patients. The resident cells in the tumour …

Stretches of cytosine-rich DNA are capable of adopting a dynamic secondary structure, the i-
motif. When within promoter regions, the i-motif has the potential to act as a molecular switch …

The lymphatic vasculature has a pivotal role in regulating body fluid homeostasis, immune
surveillance and dietary fat absorption. The increasing number of in vitro and in vivo studies …

Lymphangiogenesis refers to the generation of new lymphatic vessels from pre-existing
ones. During development and particular adult states, lymphatic endothelial cells (LEC) …

Impaired wound healing is of the most conspicuous characteristics of diabetic mellitus.
Reduced blood flow, chronic inflammatory reactions, infection, endothelial dysfunction …

Therapeutic modulation of vascular cell proliferation and migration is essential for the
effective inhibition of angiogenesis in cancer or its induction in cardiovascular disease. The …

Metastasis remains the major obstacle to improved survival for breast cancer patients.
Downregulation of FOXO3a transcription factor in breast cancer is causally associated with …

Obesity and its comorbidities like diabetes, hypertension and other cardiovascular disorders
are the leading causes of death and disability worldwide. Metabolic diseases cause …

Endothelial cells (ECs) constitute small capillary blood vessels and contribute to delivery of
nutrients, oxygen and cellular components to the local tissues, as well as to removal of …