A Vegfc-Emilin2a-Cxcl8a signaling axis required for zebrafish cardiac regeneration

H El-Sammak, B Yang, S Guenther, W Chen… - Circulation …, 2022 - Am Heart Assoc
Background: Ischemic heart disease following the obstruction of coronary vessels leads to
the death of cardiac tissue and the formation of a fibrotic scar. In contrast to adult mammals …

[HTML][HTML] Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function

L Ducoli, M Detmar - Developmental Cell, 2021 - cell.com
The lymphatic vascular system acts as the major transportation highway of tissue fluids, and
its activation or impairment is associated with a wide range of diseases. There has been …

Toxicity of chronic waterborne zinc exposure in the hepatopancreas of white shrimp Litopenaeus vannamei

Z Liang, T Chen, F Yang, S Li, S Zhang, H Guo - Chemosphere, 2022 - Elsevier
Zinc (Zn) is necessary for the survival of aquatic organisms; nevertheless, the accumulation
of Zn in excessive amounts may have toxic consequences. Few studies focusing on the …

Anti-VEGF agents: As appealing targets in the setting of COVID-19 treatment in critically ill patients

A Sahebnasagh, SM Nabavi, HRK Kashani… - International …, 2021 - Elsevier
Recently, the medications used for the severe form of the coronavirus disease-19 (COVID-
19) therapy are of particular interest. In this sense, it has been supposed that anti-VEGF …

Angiogenesis and functional vessel formation induced by interstitial flow and vascular endothelial growth factor using a microfluidic chip

Y Liu, J Li, J Zhou, X Liu, H Li, Y Lu, B Lin, X Li, T Liu - Micromachines, 2022 - mdpi.com
Angiogenesis occurs during both physiological and pathological processes. In this study, a
microfluidic chip for the development of angiogenesis was utilized to assess angiogenic …

Exosomes derived from human umbilical cord mesenchymal stem cells regulate lymphangiogenesis via the miR-302d-3p/VEGFR3/AKT axis to ameliorate …

L Zhang, J Yuan, DKW Ocansey, B Lu, A Wan… - International …, 2022 - Elsevier
Background Exosomes released from human umbilical cord mesenchymal stem cell
(hucMSC-Ex) have been revealed to hold great potential for the development of new …

[HTML][HTML] Galectins as modulators of receptor tyrosine kinases signaling in health and disease

N Porębska, M Poźniak, A Matynia, D Żukowska… - Cytokine & Growth …, 2021 - Elsevier
Receptor tyrosine kinases (RTKs) constitute a large group of cell surface proteins that
mediate communication of cells with extracellular environment. RTKs recognize external …

Collagen fibers provide guidance cues for capillary regrowth during regenerative angiogenesis in zebrafish

A Senk, V Djonov - Scientific reports, 2021 - nature.com
Although well investigated, the importance of collagen fibers in supporting angiogenesis is
not well understood. In this study, we demonstrate that extracellular collagen fibers provide …

Potential impact of microRNA gene polymorphisms in the pathogenesis of diabetes and atherosclerotic cardiovascular disease

I Elfaki, R Mir, MM Mir, FM AbuDuhier… - Journal of personalized …, 2019 - mdpi.com
MicroRNAs (miRNAs) are endogenous, small (18–23 nucleotides), non-coding RNA
molecules. They regulate the posttranscriptional expression of their target genes. MiRNAs …

An update on the potential application of herbal medicine in promoting angiogenesis

J Li, R Li, X Wu, C Zheng, PHT Shiu… - Frontiers in …, 2022 - frontiersin.org
Angiogenesis, the formation of new capillaries from pre-existing vascular networks, plays an
important role in many physiological and pathological processes. The use of pro-angiogenic …