Antiretroviral treatment (ART) has transformed human immunodeficiency virus (HIV) from a
deadly disease to a chronic illness that potentially has little effect on life expectancy. Modern …

Antiretroviral therapy has largely transformed HIV infection into a chronic disease condition.
As such, physicians and other providers caring for individuals living with HIV infection need …

T cell immunity is essential for the control of tuberculosis (TB), an important disease of the
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …

Objectives: Despite successful antiretroviral therapy, people living with HIV (PLWH) may
show signs of premature/accentuated aging. We compared established biomarkers of aging …

In the last decade, studies in persons with HIV (PWH) on antiretroviral therapy (ART) have
shed light on the significance of persistently high CD8 counts and low CD4/CD8 ratios. A …

Background Immune restoration is often incomplete after ART in HIV patients, both
quantitatively and qualitatively. We studied the incidence and probability of CD4/CD8 …

Dendritic cells (DCs) function as a link between innate and adaptive immune responses.
Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to …

Background While a low CD4/CD8 ratio during HIV treatment correlates with
immunosenescence, its value in identifying patients at an increased risk for clinical events …

Although the initial reports of increased cardiovascular (CV) disease in the setting of
advanced AIDS were reported approximately 30 years ago, advances in antiretroviral …

Starting from December 2019, the COVID-19 pandemic has globally strained medical
resources and caused significant mortality. It is commonly recognized that the severity of …