Multiple approaches have been developed to combat bacterial resistance. However, the
combination of antibiotic resistance mechanisms by bacteria and the limited number of …

Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic
resistance among pathogens. This review aims to give an overview of the major horizontal …

Soon after their discovery in the early 20th century, bacteriophages were recognized to have
great potential as antimicrobial agents, a potential that has yet to be fully realized. The …

Antibiotic resistance continues to plague antimicrobial chemotherapy of infectious disease.
And while true biocide resistance is as yet unrealized, in vitro and in vivo episodes of …

Antibiotic resistance can be achieved by horizontal acquisition of resistance genes (carried
by plasmids or transposons), by recombination of foreign DNA into the chromosome, or by …

The emergence of resistance to antibacterial agents is a pressing concern for human health.
New drugs to combat this problem are therefore in great demand, but as past experience …

It has been widely assumed that the ecological function of antibiotics in nature is fighting
against competitors. This made them a good example of the Darwinian struggle-for-life in the …

Pseudomonas aeruginosa is an opportunistic human pathogen characterized by an innate
resistance to multiple antimicrobial agents. A major contribution to this intrinsic multidrug …

Infections have been the major cause of disease throughout the history of human
populations. With the introduction of antibiotics, it was thought that this problem should …

Antibiotic resistance is one of the few examples of evolution that can be addressed
experimentally. The present review analyses this resistance, focusing on the networks that …