Previous studies have demonstrated that chronic mechanical strain produced by continuous
positive airway pressure (CPAP) reduces in vivo airway reactivity in rabbits and ferrets. For …

Asthma has been identified as a possible risk factor for Obstructive Sleep Apnea (OSA) in
children. It is not known whether parent-reported asthma increases the likelihood of the …

Background. Asthma is a known co-morbid factor in childhood obstructive sleep apnea
(OSA); however, little is known about the effects that asthma might have on the severity of …

BACKGROUND: Recent data suggest that obstructive sleep apnea (OSA) is an important
contributor to severe uncontrolled asthma. OBJECTIVE: To investigate the clinical …

Purpose Hypoxia/reoxygenation episodes in obstructive sleep apnea (OSA) results in the
alteration of the oxidative balance, leading to the development of inflammation. Airway wall …

The term overlap syndrome (OVS) in sleep disorders is used to describe the association of
obstructive sleep apnea syndrome (OSAS) with one of the following disorders: Chronic …

Historically, asthma guidelines recommend assessing and treating comorbid conditions in
order to achieve asthma control. Recent guidelines from the European Respiratory …

This study investigated whether intermittent hypoxia (IH) induces airway
hyperresponsiveness (AHR) and associated with lung inflammation. Male Brown Norway …

Background Obstructive sleep apnea syndrome (OSAS) is highly related with asthma from
the epidemiology to pathogenesis, while the underlying mechanism is still unclear. Herein …

Obstructive sleep apnea (OSA), manifested by exposure to chronic intermittent hypoxia
(CIH) and excess production of reactive oxygen species (ROS) in the airways, is associated …