Natural antioxidants are a very large diversified family of molecules classified by activity
(enzymatic or nonenzymatic), chemical-physical properties (eg, hydrophilic or lipophilic) …

Millions of people worldwide are affected by neurodegenerative diseases (NDs). NDs are
characterized by progressive damage and death of nerve cells accompanied by high levels …

The aging population is a significant social, medical and economic problem due to
increasing prevalence of chronic diseases in elderly population. Alzheimer's disease (AD) is …

Despite the fact that the small atypical serine/threonine cyclin-dependent kinase 5 (Cdk5) is
expressed in a number of tissues, its activity is restricted to the central nervous system due to …

Mitochondrial dysfunction, oxidative stress, inflammation and glucose dysmetabolism are
pathological signs of Alzheimer's disease (AD). Dietary aluminum (Al) overload is often used …

In Parkinson's disease, aggregates of α-synuclein within Lewy bodies and Lewy neurites
represent neuropathological hallmarks. However, the cellular and molecular mechanisms …

Conjugated linoleic acid (CLA) is an isomer of linoleic acid (LA). The predominant dietary
CLA is cis-9, trans-11-CLA (c-9, t-11-CLA), which constitutes up to~ 90% of total CLA and is …

Cognitive impairment (CI), mainly Alzheimer's disease (AD), continues to increase in
prevalence and is emerging as one of the major health problems in society. However, until …

Novel monoterpene-based hydroxamic acids of two structural types were synthesized for the
first time. The first type consisted of compounds with a hydroxamate group directly bound to …

Nonsteroidal anti-inflammatory drugs (NSAIDs) regulate inflammation, which is associated
with their role in preventing neurodegenerative diseases in epidemiological studies. It has …