Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Colorectal cancer and gut microbiota studies in China

Z Wang, W Dan, N Zhang, J Fang, Y Yang - Gut Microbes, 2023 - Taylor & Francis
Colorectal cancer (CRC) is the third most common malignant tumor worldwide. The
incidence and mortality rates of CRC have been increasing in China, possibly due to …

Faecal microbiome-based machine learning for multi-class disease diagnosis

Q Su, Q Liu, RI Lau, J Zhang, Z Xu, YK Yeoh… - Nature …, 2022 - nature.com
Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …

Identification of microbial markers across populations in early detection of colorectal cancer

Y Wu, N Jiao, R Zhu, Y Zhang, D Wu, AJ Wang… - Nature …, 2021 - nature.com
Associations between gut microbiota and colorectal cancer (CRC) have been widely
investigated. However, the replicable markers for early-stage adenoma diagnosis across …

GMrepo v2: a curated human gut microbiome database with special focus on disease markers and cross-dataset comparison

D Dai, J Zhu, C Sun, M Li, J Liu, S Wu… - Nucleic acids …, 2022 - academic.oup.com
GMrepo (data repository for Gut Microbiota) is a database of curated and consistently
annotated human gut metagenomes. Its main purposes are to increase the reusability and …

[HTML][HTML] Meta-analysis of the gut microbiota in predicting response to cancer immunotherapy in metastatic melanoma

A Limeta, B Ji, M Levin, F Gatto, J Nielsen - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Identifying factors conferring responses to therapy in cancer is critical to
select the best treatment for patients. For immune checkpoint inhibition (ICI) therapy …

Meta-analysis of altered gut microbiota reveals microbial and metabolic biomarkers for colorectal cancer

N Avuthu, C Guda - Microbiology Spectrum, 2022 - Am Soc Microbiol
Colorectal cancer (CRC) is the second leading cause of cancer mortality worldwide. The
dysbiotic gut microbiota and its metabolite secretions play a significant role in CRC …

Advances in tests for colorectal cancer screening and diagnosis

SCH Chan, JQ Liang - Expert review of molecular diagnostics, 2022 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related deaths
globally. Nonetheless, with early detection of CRC or its precancerous lesions, mortality, and …

[HTML][HTML] Epidemiology and risk factors of colorectal cancer in China

Y Yang, Z Han, X Li, A Huang, J Shi… - Chinese Journal of …, 2020 - ncbi.nlm.nih.gov
In China, colorectal cancer (CRC) ranked fourth and fifth in the highest incidence and
mortality rates of all malignancies in 2018, respectively. Although these rates are below the …

The human microbiome and cancer: a diagnostic and therapeutic perspective

S Kandalai, H Li, N Zhang, H Peng… - Cancer Biology & …, 2023 - Taylor & Francis
Recent evidence has shown that the human microbiome is associated with various
diseases, including cancer. The salivary microbiome, fecal microbiome, and circulating …