Cytotoxic drugs have long been recognised to kill cancer cells through apoptosis. According
to a current study, pyroptosis inhibits cell proliferation and shrinks tumors. Pyroptosis and …

Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

Significant progress has been achieved in the treatment of metastatic colorectal cancer
(mCRC) patients during the last 20 years. There are currently numerous treatments …

Background Cuproptosis induced by FDX1 is a newly discovered mechanism regulating cell
death. However, the role of FDX1 in the pathogenesis of colon adenocarcinoma (COAD) …

Genetically engineered microbes, especially Escherichia coli, have been widely used in the
biosynthesis of proteins and metabolites for medical and industrial applications. As a …

Abstract Ethnopharmacological relevance The Qi-Qin-Hu-Chang Formula (QQHCF) is a
traditional Chinese medicine prescription that is clinically used at the Affiliated Hospital of …

Background Colorectal cancer (CRC) is the third most common cancer in the world and the
second leading cause of cancer-related deaths, and over the past two decades, many of …

The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …

Colorectal cancer (CRC) is a prevalent and life-threatening cancer closely associated with
the gut microbiota. Probiotics, as a vital microbiota group, interact with the host's colonic …

Background Lactate accumulation leads to an acidic tumor microenvironment (TME), in turn
promoting colorectal cancer (CRC) progression. Tumor-associated macrophages (TAMs) …