Protein kinases (PKs), one of the largest protein families, can be further divided into different
groups based on their substrate or structure and function. PKs are important signaling …

The human gut microbiota is a complex ecosystem regulating the host's environmental
interaction. The same functional food or drug may have varying bioavailability and distinct …

The liver is essential for metabolic homeostasis. The onset of liver cancer is often
accompanied by dysregulated liver function, leading to metabolic rearrangements …

Immunotherapy, which aims to enhance the function of T cells, has emerged as a novel
therapeutic approach for hepatocellular carcinoma (HCC). Nevertheless, the clinical utility of …

Oxylipins have garnered increasing attention because they were consistently shown to play
pathological and/or pharmacological roles in the development of multiple cancers. Oxylipins …

Natural killer (NK) cells play a crucial role in immune response against viral infections and
tumors. However, further investigation is needed to better understand the key molecules …

Hepatocellular carcinoma (HCC) is the third most lethal cancer in the world. Recent studies
have shown that suppression of autophagy plays an important role in the development of …

Natural killer (NK) cells exert an indispensable role in innate immune responses against
cancer progression, however NK cell dysfunction has been rarely reported in hepatocellular …

Background An increasing number of studies have reported the involvement of oncogenes
in the regulation of the immune system. LAIR1 is an immunosuppressive molecule and its …

Despite that colorectal and liver cancer are among the most prevalent tumours in the world,
the identification of non-invasive biomarkers to aid on their diagnose and subsequent …