[HTML][HTML] Molecular and cellular mechanisms of pulmonary fibrosis
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …
Glucocorticosteroids: current and future directions
PJ Barnes - British journal of pharmacology, 2011 - Wiley Online Library
Glucocorticoids are the most effective anti‐inflammatory therapy for asthma yet are relatively
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …
Inhaled corticosteroids in COPD and the risk of serious pneumonia
Background Inhaled corticosteroids (ICS) are known to increase the risk of pneumonia in
patients with chronic obstructive pulmonary disease (COPD). It is unclear whether the risk of …
patients with chronic obstructive pulmonary disease (COPD). It is unclear whether the risk of …
Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns
D Price, D West, G Brusselle… - … journal of chronic …, 2014 - Taylor & Francis
Background Despite the availability of national and international guidelines, evidence
suggests that chronic obstructive pulmonary disease (COPD) treatment is not always …
suggests that chronic obstructive pulmonary disease (COPD) treatment is not always …
Efficacy and safety of once-daily QVA149 compared with twice-daily salmeterol–fluticasone in patients with chronic obstructive pulmonary disease (ILLUMINATE): a …
CF Vogelmeier, ED Bateman, J Pallante… - The Lancet …, 2013 - thelancet.com
Background QVA149 is an inhaled fixed-dose combination therapy under development for
the treatment of chronic obstructive pulmonary disease (COPD). It combines indacaterol (a …
the treatment of chronic obstructive pulmonary disease (COPD). It combines indacaterol (a …
Inhaled corticosteroids and the risks of diabetes onset and progression
BACKGROUND:: Systemic corticosteroids are known to increase diabetes risk, but the
effects of high-dose inhaled corticosteroids are unknown. We assessed whether the use and …
effects of high-dose inhaled corticosteroids are unknown. We assessed whether the use and …
[HTML][HTML] Inhaled corticosteroids
PJ Barnes - Pharmaceuticals, 2010 - mdpi.com
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress
inflammation mainly by switching off multiple activated inflammatory genes through …
inflammation mainly by switching off multiple activated inflammatory genes through …
LANTERN: a randomized study of QVA149 versus salmeterol/fluticasone combination in patients with COPD
N Zhong, C Wang, X Zhou, N Zhang… - … journal of chronic …, 2015 - Taylor & Francis
Background The current Global initiative for chronic Obstructive Lung Disease (GOLD)
treatment strategy recommends the use of one or more bronchodilators according to the …
treatment strategy recommends the use of one or more bronchodilators according to the …
Long‐acting muscarinic antagonist (LAMA) plus long‐acting beta‐agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive …
N Horita, A Goto, Y Shibata, E Ota… - Cochrane Database …, 2017 - cochranelibrary.com
Background Three classes of inhaler medications are used to manage chronic obstructive
pulmonary disease (COPD): long‐acting beta‐agonists (LABA), long‐acting muscarinic …
pulmonary disease (COPD): long‐acting beta‐agonists (LABA), long‐acting muscarinic …
The inevitable drift to triple therapy in COPD: an analysis of prescribing pathways in the UK
G Brusselle, D Price, K Gruffydd-Jones… - … journal of chronic …, 2015 - Taylor & Francis
Background Real-world prescription pathways leading to triple therapy (TT)(inhaled
corticosteroid [ICS] plus long-acting β2-agonist bronchodilator [LABA] plus long-acting …
corticosteroid [ICS] plus long-acting β2-agonist bronchodilator [LABA] plus long-acting …