The Role of 17β-Estradiol and Estrogen Receptors in Regulation of Ca2+ Channels and Mitochondrial Function in Cardiomyocytes
S Mahmoodzadeh, E Dworatzek - Frontiers in Endocrinology, 2019 - frontiersin.org
Numerous epidemiological, clinical, and animal studies showed that cardiac function and
manifestation of cardiovascular diseases (CVDs) are different between males and females …
manifestation of cardiovascular diseases (CVDs) are different between males and females …
Female heart health: is GPER the missing link?
The G Protein-Coupled Estrogen Receptor (GPER) is a novel membrane-bound receptor
that mediates non-genomic actions of the primary female sex hormone 17β-estradiol …
that mediates non-genomic actions of the primary female sex hormone 17β-estradiol …
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway
Z Feng, C Wang, Y Jin, Q Meng, J Wu… - Pharmaceutical …, 2021 - Taylor & Francis
Context The effect of kaempferol, a regulator of oestrogen receptors, on atherosclerosis (AS)
and the underlying mechanism is elusive. Objective To explore the effect and mechanism of …
and the underlying mechanism is elusive. Objective To explore the effect and mechanism of …
Estrogen and calcium handling proteins: new discoveries and mechanisms in cardiovascular diseases
L Jiao, JO Machuki, Q Wu, M Shi, L Fu… - American Journal …, 2020 - journals.physiology.org
Estrogen deficiency is considered to be an important factor leading to cardiovascular
diseases (CVDs). Indeed, the prevalence of CVDs in postmenopausal women exceeds that …
diseases (CVDs). Indeed, the prevalence of CVDs in postmenopausal women exceeds that …
Connecting sex differences, estrogen signaling, and microRNAs in cardiac fibrosis
Sex differences are evident in the pathophysiology of heart failure (HF). Progression of HF is
promoted by cardiac fibrosis and no fibrosis-specific therapies are currently available. The …
promoted by cardiac fibrosis and no fibrosis-specific therapies are currently available. The …
The Relationship between cadmium exposure and mortality in postmenopausal females: A cohort study of 2001–2018 NHANES
JW Shi, DX Fan, MQ Li - Nutrients, 2023 - mdpi.com
Cadmium is one of the most harmful elements to human health, and the health of
postmenopausal females is an important public health issue. However, the correlation …
postmenopausal females is an important public health issue. However, the correlation …
Sex as biological variable in cardiac mitochondrial bioenergetic responses to acute stress
Cardiac dysfunction/damage following trauma, shock, sepsis, and ischemia impacts clinical
outcomes. Acute inflammation and oxidative stress triggered by these injuries impair …
outcomes. Acute inflammation and oxidative stress triggered by these injuries impair …
Lung cancer screening CT-based coronary artery calcification in predicting cardiovascular events: a systematic review and meta-analysis
L Fan, K Fan - Medicine, 2018 - journals.lww.com
Background: Coronary artery calcificition (CAC) is a well-established predictor of
cardiovascular events (CVEs). We aimed to evaluate whether lung cancer screening …
cardiovascular events (CVEs). We aimed to evaluate whether lung cancer screening …
The effects of alone and combination tamoxifen, raloxifene and estrogen on lipid profile and atherogenic index of ovariectomized type 2 diabetic rats
Introduction The cardiovascular dysfunctions in postmenopausal diabetic women increase
relative to premenopausal women. In this study we evaluated protective effects of selective …
relative to premenopausal women. In this study we evaluated protective effects of selective …
Sex-specific determinants of coronary artery disease and atherosclerotic risk factors: estrogen and beyond
RD Feldman - Canadian Journal of Cardiology, 2020 - Elsevier
The way we view coronary artery disease in women has changed dramatically over the past
decades. From an initial perspective that coronary artery disease was a male disorder and …
decades. From an initial perspective that coronary artery disease was a male disorder and …