Mortality associated with statin use has been reported in prostate cancer (PCa) patients
treated with androgen deprivation therapy (ADT) or definitive therapy in several …

Despite recent advances in modern medicine, castration-resistant prostate cancer remains
an incurable disease. Subpopulations of prostate cancer cells develop castration-resistance …

Background/Aim: Statins are cholesterol-lowering drugs that have been shown to possess
anti-tumour properties. Observational studies have shown that 3-hydroxy-3-methlyglutaryl …

We read with great interest the article by Denkert et al.[1] about the prognostic role of Ki67
among breast cancer patients treated with neoadjuvant therapy. We think, however, that the …

Background Improved prostate cancer (PCa) survival by statin use has been reported
among PCa patients managed with radiation or androgen deprivation therapy (ADT), while …

There have been several studies that have linked elevated scavenger receptor class b type
1 (SR-B1) expression and activity to the development and progression of castration-resistant …

Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) are currently among the
most commonly prescribed pharmaceutical agents worldwide. Apart from their well …

Purpose To evaluate the association between the use of statins and/or metformin and
patient survival in prostate cancer patients in Taiwan. Subjects and methods Newly …

Recent studies suggest that statin may benefit cancer prognosis, especially through its
radiosensitization effect. But controversy exists in other studies. Hence, we performed a …

Objective Even though the exact mechanism is largely unknown until now, statins are
supposed to improve survival outcomes in various malignancies. For prostate cancer …