[HTML][HTML] Functional and biochemical consequences of disease variants in neurotransmitter transporters: a special emphasis on folding and trafficking deficits

S Bhat, A El-Kasaby, M Freissmuth, S Sucic - Pharmacology & therapeutics, 2021 - Elsevier
Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the
monoamines, facilitate the crosstalk within the central nervous system. The designated …

[图书][B] Principles of animal nutrition

G Wu - 2017 - taylorfrancis.com
Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

[HTML][HTML] Digestion and absorption of milk phospholipids in newborns and adults

Å Nilsson, RD Duan, L Ohlsson - Frontiers in nutrition, 2021 - frontiersin.org
Milk polar lipids provide choline, ethanolamine, and polyunsaturated fatty acids, which are
needed for the growth and plasticity of the tissues in a suckling child. They may also inhibit …

The neuroscience of cognitive-motivational styles: Sign-and goal-trackers as animal models.

M Sarter, KB Phillips - Behavioral neuroscience, 2018 - psycnet.apa.org
Cognitive-motivational styles describe predominant patterns of processing or biases that
broadly influence human cognition and performance. Here we focus on the impact of …

Acetylcholine regulates pulmonary pathology during viral infection and recovery

AP Horkowitz, AV Schwartz, CA Alvarez… - ImmunoTargets and …, 2020 - Taylor & Francis
Introduction This study was designed to explore the role of acetylcholine (ACh) in pulmonary
viral infection and recovery. Inflammatory control is critical to recovery from respiratory viral …

Unresponsive choline transporter as a trait neuromarker and a causal mediator of bottom-up attentional biases

AK Cherian, A Kucinski, K Pitchers, B Yegla… - Journal of …, 2017 - Soc Neuroscience
Some rats [sign-trackers (STs)] are prone to attribute incentive salience to reward cues,
which can manifest as a propensity to approach and contact pavlovian cues, and for …

Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration

CR Fagerberg, A Taylor, F Distelmaier, HD Schrøder… - Brain, 2020 - academic.oup.com
Cerebral choline metabolism is crucial for normal brain function, and its homoeostasis
depends on carrier-mediated transport. Here, we report on four individuals from three …

The hot 'n'cold of cue-induced drug relapse

KK Pitchers, M Sarter, TE Robinson - Learning & Memory, 2018 - learnmem.cshlp.org
Environmental cues associated with rewards can acquire motivational properties. However,
there is considerable variation in the extent to which a reward cue gains motivational control …

[HTML][HTML] Modulation of sodium-coupled choline transporter CHT function in health and disease

OA Ojiakor, RJ Rylett - Neurochemistry international, 2020 - Elsevier
The sodium-coupled high-affinity choline transporter CHT plays a critical role in
acetylcholine (ACh) synthesis by taking up the substrate choline from the synaptic cleft after …

Disrupted choline clearance and sustained acetylcholine release in vivo by a common choline transporter coding variant associated with poor attentional control in …

E Donovan, C Avila, S Klausner, V Parikh… - Journal of …, 2022 - Soc Neuroscience
Transport of choline via the neuronal high-affinity choline transporter (CHT; SLC5A7) is
essential for cholinergic terminals to synthesize and release acetylcholine (ACh). In humans …