Stroke remains a devastating disease with limited treatment options, despite our growing
understanding of its pathology. While ischemic stroke is traditionally characterized by a …

Retinal ischemia–reperfusion (I/R) injury is a common cause of visual impairment. To date,
no effective treatment is available for retinal I/R injury. In addition, the precise pathological …

Ischemia-induced cerebral injury is a major cause of dementia or death worldwide. The pre-
diagnosis is still challenging due to the retarded symptoms. The retina is regarded as the …

Limb remote ischemic postconditioning (LRIP) has been confirmed to reduce the ischemia-
reperfusion injury but its mechanisms are still not clear. This study clarified the mechanism of …

Cerebral and retinal ischemia share similar pathogenesis and epidemiology, each carrying
both acute and prolonged risk of the other and often co-occurring. The most used preclinical …

Research on attenuating the structural and functional deficits observed following ischemia‐
reperfusion has become increasingly focused on the therapeutic potential of ischemic …

Background To investigate retinal neurovascular structural changes in patients with
ischemic stroke (IS) using optical coherence tomography angiography (OCTA). Materials …

Retina, one of the highest oxygen demanding tissues, is vulnerable to vascular
insufficiencies, and various ocular vascular disorders can cause chronic retinal ischemia. To …

Background and Purpose—Retinal ischemia is a major cause of visual impairment in stroke
patients, but our incomplete understanding of its pathology may contribute to a lack of …

Oxidative stress is a great challenge to neurons following cerebral ischemia. PGC-1α has
been shown to act as a potent modulator of oxidative metabolism. In this study, the effects of …