Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan

A Agustí, E Melén, DL DeMeo… - The Lancet …, 2022 - thelancet.com
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …

What does endotyping mean for treatment in chronic obstructive pulmonary disease?

A Agustí, B Celli, R Faner - The Lancet, 2017 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
both at the clinical and biological level. However, COPD is still diagnosed and treated …

Gut microbiota dysbiosis contributes to the development of chronic obstructive pulmonary disease

N Li, Z Dai, Z Wang, Z Deng, J Zhang, J Pu, W Cao… - Respiratory …, 2021 - Springer
Background Dysbiosis of the gut microbiome is involved in the pathogenesis of various
diseases, but the contribution of gut microbes to the progression of chronic obstructive …

Network analysis of lung transcriptomics reveals a distinct B-cell signature in emphysema

R Faner, T Cruz, T Casserras… - American journal of …, 2016 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic
airflow limitation caused by a combination of airways disease (bronchiolitis) and …

Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue

JD Morrow, X Zhou, T Lao, Z Jiang, DL DeMeo… - Scientific reports, 2017 - nature.com
In comparison to genome-wide association studies (GWAS), there has been poor replication
of gene expression studies in chronic obstructive pulmonary disease (COPD). We performed …

Quantification of lung PET images: challenges and opportunities

DL Chen, J Cheriyan, ER Chilvers… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)

T Cruz, A López-Giraldo, G Noell… - Respiratory …, 2019 - Springer
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is associated with an
abnormal pulmonary and systemic immune response to tobacco smoking. Yet, how do …

Rice Bran Oil Improves Emphysema in Cigarette Smoke Extract-Induced Mice through Anti-Inflammatory and Antioxidative Effects

A Kettawan, S Ruangklai, T Rungruang, J Thongam… - Nutrients, 2024 - mdpi.com
Lung inflammation and alveolar enlargement are the major pathological conditions of
chronic obstructive pulmonary disease (COPD) patients. Rice bran oil (RBO), a natural anti …

Особенности иммунного реагирования при вирусных инфекциях

АГ Борисов, АА Савченко… - Инфекция и иммунитет, 2015 - cyberleninka.ru
Целью исследования явилось выделение с помощью кластерного анализа и
сравнительная характеристика типов иммунных нарушений при острых и хронических …

Кластерный анализ типов иммунных нарушений при инфекционно-воспалительных заболеваниях

АГ Борисов - Российский иммунологический журнал, 2014 - elibrary.ru
С целью выделения с помощью кластерного анализа и характеристики типов
иммунных нарушений при различных инфекционно-воспалительных заболеваниях …