Various forms of fibrosis, comprising tissue thickening and scarring, are involved in 40% of
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to …

Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

In the last decade, the advent of 3D printing for tissue engineering and regenerative
medicine has engendered great interest for those involved in skin repair and regeneration …

Skeletal muscle regeneration involves coordinated interactions between different cell types.
Injection of platelet-rich plasma is circumstantially considered an aid to muscle repair but …

Aims Biologically active molecules cytokines and growth factors (GFs) are critical regulators
of tissue injury/repair and emerge as key players in COVID-19 pathophysiology. However …

Growth factors (GFs) are versatile signalling molecules that orchestrate the dynamic, multi-
stage process of wound healing. Delivery of exogenous GFs to the wound milieu to mediate …

Cardiovascular diseases such as myocardial infarction (MI) are among the major causes of
death worldwide. Although intramyocardial injection of hydrogels can effectively enhance …

Effective antimicrobial preparations, other than antibiotics, are important for the treatment of
potentially fatal drug-resistant infections. Methicillin-resistant Staphylococcus aureus …

Platelet-rich plasma (PRP) has gained growing popularity in the treatment of articular
cartilage lesions in the last decade. However, the potential harmful effects of leukocytes in …

The morpho-functional recovery of injured skeletal muscle still represents an unmet need.
None of the therapeutic options so far adopted have proved to be resolutive. A current …