Access to pain management is a fundamental human right for all people, including those
who are at the end of life (EOL). In end-stage patients, severe and uncontrolled pain is a …

The N-methyl-D-aspartate (NMDA) glutamate receptors function as plasma membrane ionic
channels and take part in very tightly controlled cellular processes activating neurogenic …

Background Analgesia is a core intervention in emergency medicine. Pain is subjective, so
patient-reported experience with pain and analgesia is essential for healthcare …

Background and Objectives: Thoracic epidural catheterization (TEC) can be both
uncomfortable and fearful for patients when performed awake with the thought that the …

Objective To compare the effectiveness and safety of ketamine and morphine in adult
patients with acute pain in emergency department (ED) by using a meta-analysis method …

Modern electroconvulsive therapy (ECT) and the approval of nasal esketamine for clinical
use have significantly improved the approach to treatment-resistant depression (TRD) …

艾司氯胺酮是N-甲基-D-天冬氨酸(NMDA) 受体的拮抗剂, 通过与NMDA 受体, 阿片受体, M
胆碱受体, 单胺受体, 腺苷受体和其他嘌呤受体相互作用发挥抗焦虑, 催眠, 镇静和镇痛作用 …

Ketamine is a fast-acting N-methyl-D-aspartate (NMDA) receptor antagonist that can be
used in a range of clinical scenarios in the pre-hospital setting and emergency department …

Acute and chronic pain remains a significant health problem worldwide. The aging of the
population has led to an increased number of individuals experiencing both acute injuries …

The Nobel Prize in Physiology or Medicine 2021, awarded for the discoveries related to
receptors for temperature and touch, is notably significant in recent scientific discourse …