Importance Lifestyle factors are important for cancer development. However, a recent study
has been interpreted to suggest that random mutations during stem cell divisions are the …

We estimate and partition genetic variation for height, body mass index (BMI), von
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …

Since ancient times, people have attributed a variety of health benefits to moderate
consumption of fermented beverages such as wine and beer, often without any scientific …

Background The relation between body weight and mortality among persons with type 2
diabetes remains unresolved, with some studies suggesting decreased mortality among …

We respond to criticisms of Mendelian randomization (MR) by Mukamal, Stampfer and Rimm
(MSR). MSR consider that MR is receiving too much attention and should be renamed. We …

Resveratrol, a phytoalexin found in grapes and other food products, was purified and shown
to have cancer chemopreventive activity in assays representing three major stages of …

Alcoholic beverages have been consumed for thousands of years, attracting great human
interest for social, personal, and religious occasions. In addition, they have long been …

In most countries, high intake of saturated fat is positively related to high mortality from
coronary heart disease (CHD). However, the situation in France is paradoxical in that there …

Flavonoids are a group of polyphenolic compounds, diverse in chemical structure and
characteristics, found ubiquitously in plants. Therefore, flavonoids are part of the human diet …

A growing interest has emerged in the beneficial effects of plant-based diets for the
prevention of cardiovascular disease, diabetes and obesity. The Mediterranean diet, one of …