Ageing processes play a major contributing role for the development of Osteoarthritis (OA).
This prototypic degenerative condition of ageing is the most common form of arthritis and is …

Pathway analysis is often the first choice for studying the mechanisms underlying a
phenotype. However, conventional methods for pathway analysis do not take into account …

Gap junctions are cell‐to‐cell junctions that are located in the basolateral surface of two
adjoining cells. A gap junction channel is composed of a family of proteins called connexins …

Gap junctional communication between cancer cells and blood capillary cells is crucial to
tumor growth and invasion. Gap junctions may transfer microRNAs (miRs) among cells …

Background Treatment failure is a critical issue in breast cancer and identifying useful
interventions that optimize current cancer therapies remains a critical unmet need …

Gap junctions are intercellular channels made of connexin proteins, mediating both
electrical and biochemical signals between cells. The ability of gap junction proteins to …

Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in the clinical practice. It
significantly contributes to the morbidity and mortality of the elderly population. Over the past …

Ovarian cancer persists to be the most lethal gynecological malignancy, demanding
rigorous treatments involving radio-chemotherapy that trigger toxicity and consequently …

A gradual loss of functional gap junction between tumor cells has been reported with
colorectal cancer (CRC) progression. Here, we explored if colon cancer cells could also …

Abstract Connexin 43 (Cx43) is an important gap junction protein in vertebrates, which has
been reported to function as a tumor suppressor in a number of organs. However, the …