Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become
an essential method for assaying hemostatic competence in liver transplantation, cardiac …

Significant cross talk occurs between inflammation and coagulation. Thus, coagulopathy is
common in sepsis, potentially aggravating the prognosis. Initially, septic patients tend to …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) are point‐of‐care
viscoelastic devices that use whole blood samples to assess coagulation and fibrinolysis …

Infection by SARS-CoV-2 is associated with a high risk of thrombosis. The laboratory
documentation of hypercoagulability and impaired fibrinolysis remains a challenge. Our aim …

The transmembrane P-glycoprotein (P-gp) pumps that efflux drugs are a major mechanism
of cancer drug resistance. They are also important in protecting normal tissue cells from …

Viscoelastic coagulation tests have been increasingly used for hemostasis management in
cardiac surgery. The ClotPro system is a novel viscoelastic device based on principles of …

Irrespective of the reason for hypoperfusion, hypocoagulable and/or hyperfibrinolytic
hemostatic aberrancies afflict up to one-quarter of critically ill patients in shock. Intensivists …

Background The coagulation system is crucial in the pathogenesis of infective endocarditis
and undergoes significant changes during course of the disease. However, little is known …

Anticoagulant drugs (ie, unfractionated heparin, low-molecular-weight heparins, vitamin K
antagonists, and direct oral anticoagulants) are widely employed in preventing and treating …