[HTML][HTML] Artemisinin-based combination treatment of falciparum malaria

F Nosten, NJ White - Defining and Defeating the Intolerable Burden …, 2007 - ncbi.nlm.nih.gov
Artemisinin-based combination treatments (ACTs) are now generally accepted as the best
treatments for uncomplicated falciparum malaria. They are rapidly and reliably effective …

Artemisinin‐based combination therapy for treating uncomplicated malaria

D Sinclair, B Zani, S Donegan… - Cochrane Database …, 2009 - cochranelibrary.com
Background The World Health Organization recommends uncomplicated P. falciparum
malaria is treated using Artemisinin‐based Combination Therapy (ACT). This review aims to …

Artemisinin combination therapy for vivax malaria

NM Douglas, NM Anstey, BJ Angus… - The Lancet infectious …, 2010 - thelancet.com
Early parasitological diagnosis and treatment with artemisinin-based combination therapies
(ACTs) are key components of worldwide malaria elimination programmes. In general, use …

Antimalarial drugs–what is in use and what is in the pipeline

M Schlitzer - Archiv der Pharmazie: An International Journal …, 2008 - Wiley Online Library
Malaria continues to be a potentially fatal threat to almost half of the world's population. In
light of this threat, the armory to fight this disease is rather limited. Resistance against the …

Clinical pharmacology of artemisinin-based combination therapies

FT Aweeka, PI German - Clinical pharmacokinetics, 2008 - Springer
Malaria, a disease transmitted by the female Anopheles mosquito, has had devastating
effects on human populations for more than 4000 years. Treatment of the disease with single …

Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites

RT Eastman, NV Dharia, EA Winzeler… - Antimicrobial agents …, 2011 - Am Soc Microbiol
The combination of piperaquine and dihydroartemisinin has recently become the official first-
line therapy in several Southeast Asian countries. The pharmacokinetic mismatching of …

Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum …

AR Hasugian, HLE Purba… - Clinical Infectious …, 2007 - academic.oup.com
Background. Antimalarial drug resistance is now well established in both Plasmodium
falciparum and Plasmodium vivax. In southern Papua, Indonesia, where both strains of …

The effect of dosing regimens on the antimalarial efficacy of dihydroartemisinin-piperaquine: a pooled analysis of individual patient data

… Resistance Network (WWARN) DP Study Group - PLoS …, 2013 - journals.plos.org
Background Dihydroartemisinin-piperaquine (DP) is increasingly recommended for
antimalarial treatment in many endemic countries; however, concerns have been raised …

Dihydroartemisinin‐piperaquine for treating uncomplicated Plasmodium falciparum malaria

B Zani, M Gathu, S Donegan, PL Olliaro… - Cochrane Database …, 1996 - cochranelibrary.com
Abstract Background The World Health Organization (WHO) recommends Artemisinin‐
based Combination Therapy (ACT) for treating uncomplicated Plasmodium falciparum …

Dihydroartemisinin/Piperaquine: a review of its use in the treatment of uncomplicated Plasmodium falciparum malaria

GM Keating - Drugs, 2012 - Springer
Artemisinin-based combination regimens are recommended by WHO for the treatment of
uncomplicated Plasmodium falciparum malaria. One such combination comprises the …