β-Blockers in hypertension, diabetes, heart failure and acute myocardial infarction: a review of the literature
JJ DiNicolantonio, H Fares, AK Niazi, S Chatterjee… - Open …, 2015 - openheart.bmj.com
β-Blockers (BBs) are an essential class of cardiovascular medications for reducing morbidity
and mortality in patients with heart failure (HF). However, a large body of data indicates that …
and mortality in patients with heart failure (HF). However, a large body of data indicates that …
Adrenoreceptors and nitric oxide in the cardiovascular system
Nitric Oxide (NO) is a small molecule that continues to attract much attention from the
scientific community. Since its discovery, it has been evident that NO has a crucial role in the …
scientific community. Since its discovery, it has been evident that NO has a crucial role in the …
Intentional overdose with cardiac arrest treated with intravenous fat emulsion and high-dose insulin
SJ Stellpflug, CR Harris, KM Engebretsen… - Clinical …, 2010 - Taylor & Francis
Introduction. Nebivolol, a beta blocker with 3–10 times more β1 cardioselectivity than
metoprolol, has caused hypotension and bradycardia in overdose. We report a nebivolol …
metoprolol, has caused hypotension and bradycardia in overdose. We report a nebivolol …
Nebivolol in the treatment of arterial hypertension
This MiniReview reports the current knowledge about the treatment of arterial hypertension
with the third‐generation beta‐adrenoceptor antagonist (BAA) nebivolol. Furthermore, it …
with the third‐generation beta‐adrenoceptor antagonist (BAA) nebivolol. Furthermore, it …
Blockade of ß-adrenergic receptors by Nebivolol enables tumor control potential for uveal melanoma in 3D tumor spheroids and 2D cultures
LS Farhoumand, H Liu, T Tsimpaki… - International Journal of …, 2023 - mdpi.com
Uveal melanoma (UM) is the most common primary cancer of the eye in adults. A new
systemic therapy is needed to reduce the high metastasis and mortality rate. As β-blockers …
systemic therapy is needed to reduce the high metastasis and mortality rate. As β-blockers …
Clinical pharmacokinetics of nebivolol: a systematic review
Nebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …
Nebivolol-induced vasodilation of renal afferent arterioles involves β3-adrenergic receptor and nitric oxide synthase activation
MG Feng, MC Prieto, LG Navar - American Journal of …, 2012 - journals.physiology.org
Nebivolol is a β1-adrenergic blocker that also elicits renal vasodilation and increases the
glomerular filtration rate (GFR). However, its direct actions on the renal microvasculature …
glomerular filtration rate (GFR). However, its direct actions on the renal microvasculature …
[HTML][HTML] Nebivolol (bystolic), a novel beta blocker for hypertension
O Hilas, D Ezzo - Pharmacy and Therapeutics, 2009 - ncbi.nlm.nih.gov
Hypertension is an asymptomatic condition of persistently elevated blood pressure (BP) that
affects approximately 50 million Americans and one billion people worldwide. 1, 2 It has …
affects approximately 50 million Americans and one billion people worldwide. 1, 2 It has …
A pharmacokinetic drug interaction study between nebivolol and paroxetine in healthy volunteers
What is known and objective Nebivolol is a highly selective beta‐blocker with additional
vasodilator properties, widely used in the clinical practice for the treatment of hypertension …
vasodilator properties, widely used in the clinical practice for the treatment of hypertension …
[HTML][HTML] Phenotypic differences in nebivolol metabolism and bioavailability in healthy volunteers
Results Nebivolol/4-OH-nebivolol AUC metabolic ratios were not characterized by a
standard normal distribution. The unique distribution emphasized the existence of two …
standard normal distribution. The unique distribution emphasized the existence of two …