Pathophysiology of hypoxic–ischemic encephalopathy: a review of the past and a view on the future
P Greco, G Nencini, I Piva, M Scioscia, CA Volta… - Acta Neurologica …, 2020 - Springer
Hypoxic–ischemic encephalopathy, also referred as HIE, is a type of brain injury or damage
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …
Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges
LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …
human neonates, and is often associated with persistent motor, sensory, and cognitive …
[HTML][HTML] Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study
PJ Lally, P Montaldo, V Oliveira, A Soe… - The Lancet …, 2019 - thelancet.com
Background In neonatal encephalopathy, the clinical manifestations of injury can only be
reliably assessed several years after an intervention, complicating early prognostication and …
reliably assessed several years after an intervention, complicating early prognostication and …
Management and investigation of neonatal encephalopathy: 2017 update
This review discusses an approach to determining the cause of neonatal encephalopathy,
as well as current evidence on resuscitation and subsequent management of hypoxic …
as well as current evidence on resuscitation and subsequent management of hypoxic …
Current and emerging therapies in the management of hypoxic ischemic encephalopathy in neonates
J Nair, VHS Kumar - Children, 2018 - mdpi.com
Neonatal hypoxic ischemic encephalopathy (HIE) presents a significant clinical burden with
its high mortality and morbidity rates globally. Therapeutic hypothermia (TH) is now standard …
its high mortality and morbidity rates globally. Therapeutic hypothermia (TH) is now standard …
Neonatal hypoxic ischemic encephalopathy: an update on disease pathogenesis and treatment
Introduction: Hypoxic ischemic encephalopathy (HIE) is the most important reason for
morbidity and mortality in term-born infants. Understanding pathophysiology of the brain …
morbidity and mortality in term-born infants. Understanding pathophysiology of the brain …
High-dose erythropoietin and hypothermia for hypoxic-ischemic encephalopathy: a phase II trial
OBJECTIVE: To determine if multiple doses of erythropoietin (Epo) administered with
hypothermia improve neuroradiographic and short-term outcomes of newborns with hypoxic …
hypothermia improve neuroradiographic and short-term outcomes of newborns with hypoxic …
New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy
Around 0.75 million babies worldwide suffer from moderate or severe hypoxic-ischemic
encephalopathy (HIE) each year resulting in around 400,000 babies with …
encephalopathy (HIE) each year resulting in around 400,000 babies with …
Neuroimaging in the term newborn with neonatal encephalopathy
JL Wisnowski, P Wintermark, SL Bonifacio… - Seminars in Fetal and …, 2021 - Elsevier
Neuroimaging is widely used to aid in the diagnosis and clinical management of neonates
with neonatal encephalopathy (NE). Yet, despite widespread use clinically, there are few …
with neonatal encephalopathy (NE). Yet, despite widespread use clinically, there are few …
Neonatal encephalopathy and hypoxic–ischemic encephalopathy
AJ Gunn, M Thoresen - Handbook of clinical neurology, 2019 - Elsevier
Acute hypoxic–ischemic encephalopathy around the time of birth remains a major cause of
death and life-long disability. The key insight that led to the modern revival of studies of …
death and life-long disability. The key insight that led to the modern revival of studies of …