Human experimental pain studies are of value to study basic pain mechanisms under
controlled conditions. The aim of this study was to investigate whether genetic variation …

The study of how individual genetic differences, known as polymorphisms, change the
pharmacokinetics and pharmacodynamics of drugs is called pharmacogenomics. As the …

Purpose Chronic pain is a life changing condition, and non-opioid treatments have been
lately introduced to overcome the addictive nature of opioid therapies and their side effects …

Over the past two decades, Opioid Use Disorder (OUD) among pregnant women has
become a major global public health concern. OUD has been characterized as a …

The medical management of pain in chronic pancreatitis continues to pose significant
challenges for clinicians caring for these patients. There are increasing data, suggesting that …

Pharmacogenomics Testing for Postoperative Pain Optimization... : JBJS Reviews
Pharmacogenomics Testing for Postoperative Pain Optimization Before Total Knee and Total …

Osteoarthritis (OA), the most common form of arthritis, causes pain and disability, as well as
emotional distress. While total joint replacement is one of the most effective treatments …

Introduction Studies have shown that genetic variation and environmental factors are
associated with individual differences in therapeutic efficacy and side effects of opioids …

This chapter presents an overview of the opioid system consisting of a wide variety of
endogenous and exogenous ligands, as well as several receptor types, which activate …

Introduction: All health professionals should be aware of the importance of evaluating pain-
fifth vital sign-in cancer patients. Peripheral and central acting analgesics are widely used to …