The clinical team attending to a patient upon a diagnosis is faced with two main questions:
what treatment, and at what dose? Clinical trials' results provide the basis for guidance and …

After decades of warfarin being the only oral anticoagulant (OAC) widely available for stroke
prevention in atrial fibrillation, four direct OACs (apixaban, dabigatran, edoxaban and …

OBJECTIVE This study assessed the clinical impact of four treatment strategies in adults with
type 1 diabetes (T1D): real-time continuous glucose monitoring (rtCGM) with multiple daily …

Precision medicine has exploited next-generation sequencing (NGS) and gene/immune-
targeted drug deployment to transform the outlook for several lethal cancers. For instance …

Continuous glucose monitoring devices have significantly improved in many respects
compared with earlier versions. As sensor accuracy improved, US Food and Drug …

Background Although there is a considerable body of knowledge about allergen
immunotherapy (AIT), there is a lack of data on the reliability of real‐world evidence (RWE) …

Introduction Sacral neuromodulation (SNM) has been used in carefully selected patients
with neurogenic lower urinary tract dysfunctions (nLUTD) for over two decades. Methods …

Background Marked variation exists in the use of genomic data in tumour diagnosis, and
optimal integration with conventional diagnostic technology remains uncertain despite …

Objective With growing availability of digital health data and technology, health-related
studies are increasingly augmented or implemented using real world data (RWD). Recent …

The use of high-dose spinal cord stimulation (HD-SCS) has increased drastically during the
past few years, with positive results. However, there remains a deficit of real-world data of …