Background: CaMKII (Ca2+/calmodulin-dependent kinase II) plays a central role in cardiac
ischemia/reperfusion (I/R) injury—an important therapeutic target for ischemic heart disease …

Background Several epidemiological studies have investigated the association between
dietary fat intake and cardiovascular disease. However, dietary recommendations based on …

Introduction Diabetes, chronic kidney disease (CKD) and cardiovascular disease (CVD) are
cardiometabolic diseases that remain amongst the leading causes of morbidity and …

Proprotein convertase subtilisin/kexin Type 9 (PCSK9) is now identified as an important and
major player in hypercholesterolaemia and atherosclerosis pathophysiology. PCSK9 …

The lymphatic vasculature, which accompanies the blood vasculature in most organs, is
indispensable in the maintenance of tissue fluid homeostasis, immune cell trafficking, and …

Ischemic cardiomyopathy (ICM) is a special type of coronary heart disease or an advanced
stage of the disease, which is related to the pathological mechanism of primary dilated …

Medical imaging is an important factor for diagnosis. It can be used to diagnose patients,
differentiate disease stages, and monitor treatment regimens. Although different imaging …

Myocardial infarction (MI) is still a major cause of mortality and morbidity worldwide.
Elastomer cardiac patches have shown great potential in preventing left ventricle (LV) …

Cardiovascular disease is a leading cause of death worldwide and is associated with
systemic inflammation. In depth study of the cell-specific signaling mechanisms mediating …

Reactive oxygen species (ROS) play an important role in the pathogenesis of numerous
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …