[HTML][HTML] Sex differences in inflammation, redox biology, mitochondria and autoimmunity

DN Di Florio, J Sin, MJ Coronado, PS Atwal… - Redox biology, 2020 - Elsevier
Autoimmune diseases are characterized by circulating antibodies and immune complexes
directed against self-tissues that result in both systemic and organ-specific inflammation and …

Genistein: Dual role in women's health

L Yu, E Rios, L Castro, J Liu, Y Yan, D Dixon - Nutrients, 2021 - mdpi.com
Advanced research in recent years has revealed the important role of nutrients in the
protection of women's health and in the prevention of women's diseases. Genistein is a …

BPA alters estrogen receptor expression in the heart after viral infection activating cardiac mast cells and T cells leading to perimyocarditis and fibrosis

KA Bruno, JE Mathews, AL Yang… - Frontiers in …, 2019 - frontiersin.org
Myocarditis is an inflammatory heart disease that leads to dilated cardiomyopathy (DCM)
and heart failure. Sex hormones play an important role in the development of myocarditis …

Vitamin d serum levels in subjects tested for SARS-CoV-2: What are the differences among acute, healed, and negative COVID-19 patients? a multicenter real …

L Gallelli, GC Mannino, F Luciani, A de Sire… - Nutrients, 2021 - mdpi.com
Vitamin D might play a role in counteracting COVID-19, albeit strong evidence is still lacking
in the literature. The present multicenter real-practice study aimed to evaluate the …

Coxsackievirus B3—its potential as an oncolytic virus

A Geisler, A Hazini, L Heimann, J Kurreck, H Fechner - Viruses, 2021 - mdpi.com
Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise
untreatable types of cancer. Despite encouraging developments in recent years, the limited …

Estrogens as regulator of hematopoietic stem cell, immune cells and bone biology

RS Kumar, N Goyal - Life Sciences, 2021 - Elsevier
Hematopoietic stem cells provide continuous supply of all the immune cells, through
proliferation and differentiation decisions. These decisions are controlled by local bone …

Sex-specific regulation of IL-10 production in human adipose tissue in obesity

N Subramanian, B Tavira, K Hofwimmer… - Frontiers in …, 2022 - frontiersin.org
Background Obesity-associated metabolic complications display sexual dimorphism and
can be impacted by cytokines. We previously showed that interleukin-10 (IL-10) was …

Sex-specific differences of the inflammatory state in experimental autoimmune myocarditis

ML Barcena, S Jeuthe, MH Niehues… - Frontiers in …, 2021 - frontiersin.org
Increasing evidence suggests male sex as a potential risk factor for a higher incidence of
cardiac fibrosis, stronger cardiac inflammation, and dilated cardiomyopathy (DCM) in human …

Estrogen receptor modulators in viral infections such as SARS− CoV− 2: therapeutic consequences

N Abramenko, F Vellieux, P Tesařová, Z Kejík… - International Journal of …, 2021 - mdpi.com
COVID-19 is a pandemic respiratory disease caused by the SARS− CoV− 2 coronavirus.
The worldwide epidemiologic data showed higher mortality in males compared to females …

Immune system sex differences may bridge the gap between sex and gender in fibromyalgia

I Meester, GF Rivera-Silva… - Frontiers in …, 2020 - frontiersin.org
The fibromyalgia syndrome (FMS) is characterized by chronic widespread pain, sleep
disturbances, fatigue, and cognitive alterations. A limited efficacy of targeted treatment and a …