Evaluation of hypersomnolence: From symptoms to diagnosis, a multidimensional approach

L Peter-Derex, JA Micoulaud-Franchi, R Lopez… - Revue …, 2023 - Elsevier
Hypersomnolence is a major public health issue given its high frequency, its impact on
academic/occupational functioning and on accidentology, as well as its heavy socio …

[HTML][HTML] Systems Biology in Cancer Diagnosis Integrating Omics Technologies and Artificial Intelligence to Support Physician Decision Making

A Fawaz, A Ferraresi, C Isidoro - Journal of Personalized Medicine, 2023 - mdpi.com
Cancer is the second major cause of disease-related death worldwide, and its accurate
early diagnosis and therapeutic intervention are fundamental for saving the patient's life …

[HTML][HTML] Epidemiology, physiology and clinical approach to sleepiness at the wheel in OSA patients: a narrative review

MR Bonsignore, C Lombardi, S Lombardo… - Journal of clinical …, 2022 - mdpi.com
Sleepiness at the wheel (SW) is recognized as an important factor contributing to road traffic
accidents, since up to 30 percent of fatal accidents have been attributed to SW. Sleepiness …

The individual and societal prices of non-adherence to continuous positive airway pressure, contributors, and strategies for improvement

M Mendelson, J Duval, F Bettega… - Expert Review of …, 2023 - Taylor & Francis
Introduction Continuous positive airway pressure (CPAP) is the first-line therapy for
obstructive sleep apnea (OSA). CPAP is highly effective for improving symptoms and quality …

Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice

C Puech, M Badran, MB Barrow, AR Runion, D Gozal - Sleep, 2023 - academic.oup.com
Obstructive sleep apnea (OSA) is a highly prevalent condition characterized by episodes of
partial or complete breath cessation during sleep that induces sleep fragmentation (SF). One …

The PAP-RES algorithm: Defining who, why and how to use positive airway pressure therapy for OSA

F Gagnadoux, E Bequignon, A Prigent… - Sleep Medicine …, 2024 - Elsevier
Obstructive sleep apnea (OSA) is a common condition that is increasing in prevalence
worldwide. Untreated OSA has a negative impact on health-related quality of life and is an …

Recommandations pour le bilan et la prise en charge de la somnolence résiduelle dans le syndrome d'apnées-hypopnées obstructives du sommeil

L Barateau, S Baillieul, C Andrejak, É Bequignon… - Médecine du …, 2023 - Elsevier
Résumé La plainte de somnolence diurne excessive (SDE) est très fréquente chez les
patients souffrant de syndrome d'apnées-hypopnées obstructives du sommeil (SAHOS). Elle …

Recommendations for clinical management of excessive daytime sleepiness in obstructive sleep apnoea–A Delphi consensus study

JS Steier, RK Bogan, IM Cano-Pumarega, JA Fleetham… - Sleep Medicine, 2023 - Elsevier
Study objective Excessive daytime sleepiness is common with obstructive sleep apnoea and
can persist despite efforts to optimise primary airway therapy. The literature lacks …

Real-world impact of continuous positive airway pressure on sleepiness in patients with obstructive sleep apnea in a national registry

P Jennum, J Kjellberg, G Carls, R Ibsen, S Mettam - Sleep Medicine, 2024 - Elsevier
Objective Excessive daytime sleepiness (EDS) persists in some patients with obstructive
sleep apnea (OSA) despite continuous positive airway pressure (CPAP) treatment. This …

Recovery Mimicking “Ideal” CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents

M Badran, C Puech, MB Barrow, AR Runion… - Archivos de …, 2023 - Elsevier
Introduction Obstructive sleep apnea (OSA) is a chronic condition characterized by
intermittent hypoxia (IH) and sleep fragmentation (SF). OSA can induce excessive daytime …