Modifiable risk factors for Alzheimer's disease
GA Edwards III, N Gamez, G Escobedo Jr… - Frontiers in aging …, 2019 - frontiersin.org
Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …
prevalence and concern. Research still drives to understand the etiology and pathogenesis …
Review of the current state of protein aggregation inhibition from a materials chemistry perspective: Special focus on polymeric materials
Protein instability caused by exposure to external additives or severe stress may result in
different diseases. Of these diseases, many are triggered by protein misfolding and …
different diseases. Of these diseases, many are triggered by protein misfolding and …
Gut microbiota and aging
Z Ling, X Liu, Y Cheng, X Yan, S Wu - Critical reviews in food …, 2022 - Taylor & Francis
Aging is characterized by the functional decline of tissues and organs and increased risk of
aging-associated disorders, which pose major societal challenges and are a public health …
aging-associated disorders, which pose major societal challenges and are a public health …
Natural polyphenolic nanodots for Alzheimer's disease treatment
The abnormal amyloid‐β accumulation is essential and obbligato in Alzheimer's disease
pathogenesis and natural polyphenols exhibit great potential as amyloid aggregation …
pathogenesis and natural polyphenols exhibit great potential as amyloid aggregation …
Inflammatory cascade in Alzheimer's disease pathogenesis: A review of experimental findings
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Most AD patients
develop the disease in late life, named late onset AD (LOAD). Currently, the most …
develop the disease in late life, named late onset AD (LOAD). Currently, the most …
Green Tea Extracts EGCG and EGC Display Distinct Mechanisms in Disrupting Aβ42 Protofibril
The amyloid beta (Aβ) fibrillar aggregate is the hallmark of Alzheimer's disease (AD).
Disassembling preformed fibril or inhibiting Aβ aggregation is considered as a therapeutic …
Disassembling preformed fibril or inhibiting Aβ aggregation is considered as a therapeutic …
Green tea epigallocatechin-3-gallate (EGCG) targeting protein misfolding in drug discovery for neurodegenerative diseases
The potential to treat neurodegenerative diseases (NDs) of the major bioactive compound of
green tea, epigallocatechin-3-gallate (EGCG), is well documented. Numerous findings now …
green tea, epigallocatechin-3-gallate (EGCG), is well documented. Numerous findings now …
Curcumin interacts with α-synuclein condensates to inhibit amyloid aggregation under phase separation
B Xu, J Chen, Y Liu - ACS omega, 2022 - ACS Publications
The amyloid aggregation of α-synuclein (α-Syn) is highly associated with Parkinson's
disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies …
disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies …
Neuroprotective effects of agri-food by-products rich in phenolic compounds
Neurodegenerative diseases are known for their wide range of harmful conditions related to
progressive cell damage, nervous system connections and neuronal death. These …
progressive cell damage, nervous system connections and neuronal death. These …
The emerging role of nutraceuticals and phytochemicals in the prevention and treatment of Alzheimer's disease
C Calfio, A Gonzalez, SK Singh… - Journal of …, 2020 - content.iospress.com
One of the major challenges of medical sciences has been finding a reliable compound for
the pharmacological treatment of Alzheimer's disease (AD). As most of the drugs directed to …
the pharmacological treatment of Alzheimer's disease (AD). As most of the drugs directed to …