[HTML][HTML] Ursolic acid's alluring journey: one triterpenoid vs. cancer hallmarks
Cancer is a multifactorial disease characterized by various hallmarks, including uncontrolled
cell growth, evasion of apoptosis, sustained angiogenesis, tissue invasion, and metastasis …
cell growth, evasion of apoptosis, sustained angiogenesis, tissue invasion, and metastasis …
[HTML][HTML] Targeted inhibitors of EGFR: structure, biology, biomarkers, and clinical applications
N Shaban, D Kamashev, A Emelianova, A Buzdin - Cells, 2023 - mdpi.com
Members of the EGFR family of tyrosine kinase receptors are major regulators of cellular
proliferation, differentiation, and survival. In humans, abnormal activation of EGFR is …
proliferation, differentiation, and survival. In humans, abnormal activation of EGFR is …
Cytoreductive surgery, systemic treatment, genetic evaluation, and patient perspective in a young adult with metastatic renal cell carcinoma
EH Nicaise, A Yildirim, S Sheth… - CA: A Cancer …, 2024 - Wiley Online Library
A man aged 41 years who had a past medical history significant for bilateral lower extremity
varicosities and a prior 20‐pack‐year smoking history reported several days of fatigue to his …
varicosities and a prior 20‐pack‐year smoking history reported several days of fatigue to his …
[HTML][HTML] Potentials and future perspectives of multi-target drugs in cancer treatment: the next generation anti-cancer agents
A Doostmohammadi, H Jooya, K Ghorbanian… - Cell Communication and …, 2024 - Springer
Cancer is a major public health problem worldwide with more than an estimated 19.3 million
new cases in 2020. The occurrence rises dramatically with age, and the overall risk …
new cases in 2020. The occurrence rises dramatically with age, and the overall risk …
Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes
JC Laguna, M Tagliamento, M Lambertini… - American Society of …, 2024 - ascopubs.org
Lung cancer has traditionally been associated with advanced age; however, its increasing
incidence among young adults raises concerning questions regarding its etiology and …
incidence among young adults raises concerning questions regarding its etiology and …
[HTML][HTML] Exploring the impact of novel anti-cancer therapies on jaw osteonecrosis and other bones: A comprehensive review
W Konarski, T Poboży, K Konarska… - Journal of Clinical …, 2024 - mdpi.com
Osteonecrosis is a debilitating condition characterized by the loss of blood supply to the
bones, leading to bone death. This condition can impact various bones, including the jaw …
bones, leading to bone death. This condition can impact various bones, including the jaw …
[HTML][HTML] Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications
Abstract Cutaneous Squamous Cell Carcinoma (cSCC) is a common and potentially fatal
type of skin cancer that poses a significant threat to public health and has a high prevalence …
type of skin cancer that poses a significant threat to public health and has a high prevalence …
Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence
The development of antifungal drugs requires novel molecular targets due to limited
treatment options and drug resistance. Through chemical screening and establishment of a …
treatment options and drug resistance. Through chemical screening and establishment of a …
[HTML][HTML] Prognostic Markers in Tyrosine Kinases Specific to Basal-like 2 Subtype of Triple-Negative Breast Cancer
P Limsakul, P Choochuen, T Jungrungrueang… - International Journal of …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC), a heterogeneous and therapeutically challenging
subtype, comprises over 50% of patients categorized into basal-like 1 (BL1) and basal-like 2 …
subtype, comprises over 50% of patients categorized into basal-like 1 (BL1) and basal-like 2 …
[HTML][HTML] The Role of Amino Acids in Non-Enzymatic Antioxidant Mechanisms in Cancer: A Review
EI Dyachenko, LV Bel'skaya - Metabolites, 2023 - mdpi.com
Currently, the antioxidant properties of amino acids and their role in the physicochemical
processes accompanying oxidative stress in cancer remain unclear. Cancer cells are known …
processes accompanying oxidative stress in cancer remain unclear. Cancer cells are known …