[HTML][HTML] Ursolic acid's alluring journey: one triterpenoid vs. cancer hallmarks

Y Limami, A Pinon, H Wahnou, M Oudghiri, B Liagre… - Molecules, 2023 - mdpi.com
Cancer is a multifactorial disease characterized by various hallmarks, including uncontrolled
cell growth, evasion of apoptosis, sustained angiogenesis, tissue invasion, and metastasis …

[HTML][HTML] Targeted inhibitors of EGFR: structure, biology, biomarkers, and clinical applications

N Shaban, D Kamashev, A Emelianova, A Buzdin - Cells, 2023 - mdpi.com
Members of the EGFR family of tyrosine kinase receptors are major regulators of cellular
proliferation, differentiation, and survival. In humans, abnormal activation of EGFR is …

Cytoreductive surgery, systemic treatment, genetic evaluation, and patient perspective in a young adult with metastatic renal cell carcinoma

EH Nicaise, A Yildirim, S Sheth… - CA: A Cancer …, 2024 - Wiley Online Library
A man aged 41 years who had a past medical history significant for bilateral lower extremity
varicosities and a prior 20‐pack‐year smoking history reported several days of fatigue to his …

[HTML][HTML] Potentials and future perspectives of multi-target drugs in cancer treatment: the next generation anti-cancer agents

A Doostmohammadi, H Jooya, K Ghorbanian… - Cell Communication and …, 2024 - Springer
Cancer is a major public health problem worldwide with more than an estimated 19.3 million
new cases in 2020. The occurrence rises dramatically with age, and the overall risk …

Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes

JC Laguna, M Tagliamento, M Lambertini… - American Society of …, 2024 - ascopubs.org
Lung cancer has traditionally been associated with advanced age; however, its increasing
incidence among young adults raises concerning questions regarding its etiology and …

[HTML][HTML] Exploring the impact of novel anti-cancer therapies on jaw osteonecrosis and other bones: A comprehensive review

W Konarski, T Poboży, K Konarska… - Journal of Clinical …, 2024 - mdpi.com
Osteonecrosis is a debilitating condition characterized by the loss of blood supply to the
bones, leading to bone death. This condition can impact various bones, including the jaw …

[HTML][HTML] Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications

H Singh, H Chopra, I Singh, S Mohanto, MG Ahmed… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Abstract Cutaneous Squamous Cell Carcinoma (cSCC) is a common and potentially fatal
type of skin cancer that poses a significant threat to public health and has a high prevalence …

Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence

M Ishii, Y Matsumoto, T Yamada, H Uga, T Katada… - iScience, 2024 - cell.com
The development of antifungal drugs requires novel molecular targets due to limited
treatment options and drug resistance. Through chemical screening and establishment of a …

[HTML][HTML] Prognostic Markers in Tyrosine Kinases Specific to Basal-like 2 Subtype of Triple-Negative Breast Cancer

P Limsakul, P Choochuen, T Jungrungrueang… - International Journal of …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC), a heterogeneous and therapeutically challenging
subtype, comprises over 50% of patients categorized into basal-like 1 (BL1) and basal-like 2 …

[HTML][HTML] The Role of Amino Acids in Non-Enzymatic Antioxidant Mechanisms in Cancer: A Review

EI Dyachenko, LV Bel'skaya - Metabolites, 2023 - mdpi.com
Currently, the antioxidant properties of amino acids and their role in the physicochemical
processes accompanying oxidative stress in cancer remain unclear. Cancer cells are known …