Applications of nanobodies

S Muyldermans - Annual review of animal biosciences, 2021 - annualreviews.org
Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are
circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via …

Surface plasmon resonance (SPR) sensor for cancer biomarker detection

S Das, R Devireddy, MR Gartia - Biosensors, 2023 - mdpi.com
A biomarker is a physiological observable marker that acts as a stand-in and, in the best-
case scenario, forecasts a clinically significant outcome. Diagnostic biomarkers are more …

Microfluidic chips for point‐of‐care immunodiagnostics

L Gervais, N De Rooij, E Delamarche - Advanced materials, 2011 - Wiley Online Library
We might be at the turning point where research in microfluidics undertaken in academia
and industrial research laboratories, and substantially sponsored by public grants, may …

General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold

C Vincke, R Loris, D Saerens… - Journal of Biological …, 2009 - ASBMB
Nanobodies, single-domain antigen-binding fragments of camelid-specific heavy-chain only
antibodies offer special advantages in therapy over classic antibody fragments because of …

[HTML][HTML] Graphene nanocomposites modified electrochemical aptamer sensor for rapid and highly sensitive detection of prostate specific antigen

B Wei, K Mao, N Liu, M Zhang, Z Yang - Biosensors and Bioelectronics, 2018 - Elsevier
Prostate specific antigen (PSA) is a widely used marker for the diagnosis of prostate cancer,
and the increasing attention has been attracted on the development of rapid assay using …

Semiconductor quantum dots and metal nanoparticles: syntheses, optical properties, and biological applications

V Biju, T Itoh, A Anas, A Sujith, M Ishikawa - Analytical and bioanalytical …, 2008 - Springer
We review the syntheses, optical properties, and biological applications of cadmium
selenide (CdSe) and cadmium selenide–zinc sulfide (CdSe–ZnS) quantum dots (QDs) and …

Cancer detection using nanoparticle-based sensors

M Perfézou, A Turner, A Merkoçi - Chemical Society Reviews, 2012 - pubs.rsc.org
This tutorial review surveys the latest achievements in the use of nanoparticles to detect
cancer biomarkers and cancer cells with a focus on optical and electrochemical techniques …

Antifouling zwitterionic peptide hydrogel based electrochemical biosensor for reliable detection of prostate specific antigen in human serum

Q Du, W Wang, X Zeng, X Luo - Analytica Chimica Acta, 2023 - Elsevier
An electrochemical biosensor based on the antifouling zwitterionic peptide hydrogel
(CFEFKFC) and the poly (3, 4-ethylenedioxythiophene)(PEDOT) was fabricated to …

Highly sensitive biosensing using arrays of plasmonic Au nanodisks realized by nanoimprint lithography

SW Lee, KS Lee, J Ahn, JJ Lee, MG Kim, YB Shin - ACS nano, 2011 - ACS Publications
We describe the fabrication of elliptical Au nanodisk arrays as a localized surface plasmon
resonance (LSPR) sensing substrate for clinical immunoassay via thermal nanoimprint …

Surface plasmon resonance for biosensing: a mini-review

I Abdulhalim, M Zourob, A Lakhtakia - Electromagnetics, 2008 - Taylor & Francis
A variety of configurations and formats have been devised to exploit the phenomenon of
surface plasmon on metal dielectric interfaces for sensing a variety of significant analytes …