Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …
more than 500 million population worldwide. OA was believed to be caused by the wearing …
Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review
R Margiana, A Markov, AO Zekiy, MU Hamza… - Stem Cell Research & …, 2022 - Springer
The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide
consideration because of their immense potential for immunomodulation and their …
consideration because of their immense potential for immunomodulation and their …
The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity
Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy
M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential
N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells that are emerging as the most
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …
Mesenchymal stem cells: amazing remedies for bone and cartilage defects
P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …
worldwide. The use of stem cells for tissue repair has raised many promises in various …
Anti‐friction MSCs delivery system improves the therapy for severe osteoarthritis
X Yan, B Yang, Y Chen, Y Song, J Ye, Y Pan… - Advanced …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a musculoskeletal disorder disease affecting about 500 million people
worldwide and mesenchymal sem cells (MSCs) therapy has been demonstrated as a …
worldwide and mesenchymal sem cells (MSCs) therapy has been demonstrated as a …
Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis
Osteoarthritis, as a degenerative disease, is a common problem and results in high
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …
Macrophage: a potential target on cartilage regeneration
Cartilage lesions and osteoarthritis (OA) presents an ever-increasing clinical and
socioeconomic burden. Synovial inflammation and articular inflammatory environment are …
socioeconomic burden. Synovial inflammation and articular inflammatory environment are …