PURPOSE The terms undertreatment and overtreatment are often used to describe
inappropriate management of older adults with cancer. We conducted a comprehensive …

Aging is accompanied by marked changes in the physiology of many organs, as well as in
their constituent cells. These nonpathological alterations in structure and/or function may …

BACKGROUND Colon carcinoma primarily affects older‐aged persons 65 years and older.
Seventy‐five percent of the incident tumors affect persons in this age group. Because of their …

In 1990, the five leading causes of cancer death in men aged 65 and older were carcinomas
of the lung, prostate, colon and rectum, and pancreas, and leukemia. For women in this age …

Purpose The majority of patients with relapsed or refractory B-cell non-Hodgkin's lymphoma
(NHL) are older than 60 years, yet they are often denied potentially curative high-dose …

As the geriatric population is growing, it is increasingly important to be familiar with
chemotherapy for the elderly. Age-related changes in pharmacokinetics are documented for …

The efficacy and toxicity of chronic administration of oral etoposide was evaluated in 61
patients with inoperable non-small-cell lung cancer (NSCLC). Ten patients received …

High-dose therapy (HDT) with autologous stem cell transplantation (ASCT) is the optimal
treatment for patients with relapsed aggressive non-Hodgkin's lymphoma (NHL). HDT …

BACKGROUND In spite of the high prevalence of cancer in the elderly, little information is
available about the efficacy and toxicity of chemotherapy in elderly patients. In a previous …

The aging of the population has focused attention on the special needs of elderly patients.
The increasing number of elderly people in the world's population has led to a parallel …