Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs–a PEARRL review
S Jankovic, G Tsakiridou, F Ditzinger… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Solubility parameters have been used for decades in various scientific fields
including pharmaceutics. It is, however, still a field of active research both on a conceptual …
including pharmaceutics. It is, however, still a field of active research both on a conceptual …
[HTML][HTML] Analysing the potential of the selective dissolution of elastane from mixed fiber textile waste
K Phan, S Ügdüler, L Harinck, R Denolf… - Resources …, 2023 - Elsevier
Textile products are composed of various blends of synthetic or natural polymers. Elastane
increases the functionality during use phase, but impedes high quality recycling. This study …
increases the functionality during use phase, but impedes high quality recycling. This study …
A Bayesian approach to predict solubility parameters
B Sanchez‐Lengeling, LM Roch… - Advanced Theory …, 2019 - Wiley Online Library
Solubility is a ubiquitous phenomenon in many aspects of material science. While solubility
can be determined by considering the cohesive forces in a liquid via the Hansen solubility …
can be determined by considering the cohesive forces in a liquid via the Hansen solubility …
Solubility prediction from molecular properties and analytical data using an in-phase deep neural network (Ip-DNN)
A Kurotani, T Kakiuchi, J Kikuchi - ACS omega, 2021 - ACS Publications
Materials informatics is an emerging field that allows us to predict the properties of materials
and has been applied in various research and development fields, such as materials …
and has been applied in various research and development fields, such as materials …
Mechanistic insights into luteolin-loaded elastic liposomes for transdermal delivery: HSPiP predictive parameters and instrument-based evidence
MA Altamimi, A Hussain, WA Mahdi, SS Imam… - ACS …, 2022 - ACS Publications
We evaluated mechanistic insights into luteolin (LUT)-loaded elastic liposomes (OLEL1)
permeated across rat skin. HSPiP software-based parameters, thermal analysis, infrared …
permeated across rat skin. HSPiP software-based parameters, thermal analysis, infrared …
The use of neural network modeling for the estimation of the Hansen solubility parameters of polymer films from contact angle measurements
N AlQasas, D Johnson - Surfaces and Interfaces, 2024 - Elsevier
A neural network model is proposed to predict the Hansen Solubility parameter (HSP) of a
polymer/solid surface via simple contact angle measuring using only three different types of …
polymer/solid surface via simple contact angle measuring using only three different types of …
[HTML][HTML] Nitrogen plasma modification boosts up the hemocompatibility of new PVDF-carbon nanohorns composite materials with potential cardiological and …
M Zięba, T Rusak, T Misztal, W Zięba, N Marcińczyk… - Biomaterials …, 2022 - Elsevier
To design new material for blood-related applications one needs to consider various factors
such as cytotoxicity, platelet adhesion, or anti-thrombogenic properties. The aim of this work …
such as cytotoxicity, platelet adhesion, or anti-thrombogenic properties. The aim of this work …
Solubility-physicochemical-thermodynamic theory of penetration enhancer mechanism of action
A Haq, M Chandler, B Michniak-Kohn - International Journal of …, 2020 - Elsevier
The hypothesis for the investigation was that the overall mechanism of action of skin
penetration enhancers is best explained by the Solubility-Physicochemical-Thermodynamic …
penetration enhancers is best explained by the Solubility-Physicochemical-Thermodynamic …
A combined mathematical model linking the formation of amorphous solid dispersions with hot-melt-extrusion process parameters
A Schittny, H Ogawa, J Huwyler, M Puchkov - European Journal of …, 2018 - Elsevier
Hot-melt extrusion allows for the continuous production of amorphous solid dispersions,
which are used to enhance bioavailability of poorly soluble drugs in pharmaceutical drug …
which are used to enhance bioavailability of poorly soluble drugs in pharmaceutical drug …
Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line
JR Campos, AR Fernandes, R Sousa… - Pharmaceutical …, 2019 - Taylor & Francis
The aim of this work is development of a nontoxic, long-term stable solid lipid nanoparticles
(SLN) formulation for the loading of Nimesulide (NiM) by a 22 factorial design. The optimized …
(SLN) formulation for the loading of Nimesulide (NiM) by a 22 factorial design. The optimized …