Recent advances in understanding enteric pathogenic Escherichia coli

MA Croxen, RJ Law, R Scholz… - Clinical microbiology …, 2013 - Am Soc Microbiol
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

The global problem of childhood diarrhoeal diseases: emerging strategies in prevention and management

M Mokomane, I Kasvosve, E Melo… - Therapeutic …, 2018 - journals.sagepub.com
Acute diarrhoeal diseases remain a leading cause of global morbidity and mortality
particularly among young children in resource-limited countries. Recent large studies …

Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study

J Liu, JA Platts-Mills, J Juma, F Kabir, J Nkeze, C Okoi… - The Lancet, 2016 - thelancet.com
Background Diarrhoea is the second leading cause of mortality in children worldwide, but
establishing the cause can be complicated by diverse diagnostic approaches and varying …

Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development

S Livio, NA Strockbine, S Panchalingam… - Clinical Infectious …, 2014 - academic.oup.com
Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development |
Clinical Infectious Diseases | Oxford Academic Skip to Main Content Advertisement Oxford …

[HTML][HTML] Emergence of antibiotic resistant Shigella species: A matter of concern

M Puzari, M Sharma, P Chetia - Journal of infection and public health, 2018 - Elsevier
A major threat to the world is the emergence of antibiotic resistant bacteria, which has
rendered previously susceptible drugs useless and increased the rate of therapeutic …

Practical guidance for clinical microbiology laboratories: diagnosis of bacterial gastroenteritis

RM Humphries, AJ Linscott - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Bacterial gastroenteritis is a disease that is pervasive in both the developing and developed
worlds. While for the most part bacterial gastroenteritis is self-limiting, identification of an …

Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion

GN Schroeder, H Hilbi - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Shigella spp. are gram-negative pathogenic bacteria that evolved from harmless
enterobacterial relatives and may cause devastating diarrhea upon ingestion. Research …

Guidelines for the treatment of dysentery (shigellosis): a systematic review of the evidence

PCM Williams, JA Berkley - Paediatrics and international child …, 2018 - Taylor & Francis
Background: Shigella remains the primary cause of diarrhoea in paediatric patients
worldwide and accounts for up to 40,000 deaths per year. Current guidelines for the …

Salmonella, Shigella, and yersinia

JP Dekker, KM Frank - Clinics in laboratory medicine, 2015 - labmed.theclinics.com
In this review, the authors discuss 3 enteric pathogens: Salmonella, Shigella, and Yersinia.
These important members of Enterobacteriaceae are responsible for significant morbidity …

Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road

MM Levine, KL Kotloff, EM Barry, MF Pasetti… - Nature Reviews …, 2007 - nature.com
More than 50 years of research has yielded numerous Shigella vaccine candidates that
have exemplified both the promise of vaccine-induced prevention of shigellosis and the …