New approaches and procedures for cancer treatment: Current perspectives

DT Debela, SGY Muzazu, KD Heraro… - SAGE open …, 2021 - journals.sagepub.com
Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …

Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer

F Ye, S Dewanjee, Y Li, NK Jha, ZS Chen, A Kumar… - Molecular cancer, 2023 - Springer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches

TB Emran, A Shahriar, AR Mahmud, T Rahman… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …

Remotely controlled near-infrared-triggered photothermal treatment of brain tumours in freely behaving mice using gold nanostar s

H Arami, S Kananian, L Khalifehzadeh, CB Patel… - Nature …, 2022 - nature.com
Current clinical brain tumour therapy practices are based on tumour resection and post-
operative chemotherapy or X-ray radiation. Resection requires technically challenging open …

Biomedical applications of iron oxide nanoparticles: current insights progress and perspectives

MG Montiel Schneider, MJ Martín, J Otarola… - Pharmaceutics, 2022 - mdpi.com
The enormous development of nanomaterials technology and the immediate response of
many areas of science, research, and practice to their possible application has led to the …

Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy

M Delfi, R Sartorius, M Ashrafizadeh, E Sharifi, Y Zhang… - Nano Today, 2021 - Elsevier
Self-assembled peptides and proteins possess tremendous potential as targeted drug
delivery systems and key applications of these well-defined nanostructures reside in anti …

Smart nanomaterials in cancer theranostics: challenges and opportunities

BK Kashyap, VV Singh, MK Solanki, A Kumar… - ACS …, 2023 - ACS Publications
Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …

Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors

S Sofi, U Mehraj, H Qayoom, S Aisha, A Almilaibary… - Medical Oncology, 2022 - Springer
Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …

Nano-based approved pharmaceuticals for cancer treatment: present and future challenges

F Rodríguez, P Caruana, N De la Fuente, P Español… - Biomolecules, 2022 - mdpi.com
Cancer is one of the main causes of death worldwide. To date, and despite the advances in
conventional treatment options, therapy in cancer is still far from optimal due to the non …