Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Mild cognitive impairment (MCI), first fully characterized by Petersen and associates in 1997,
1 generally refers to impairment in cognition above that which is seen with normal age …

Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer's disease (AD), causing
substantial distress for both people with dementia and their caregivers, and contributing to …

Neuropsychiatric symptoms (NPS) are common in dementia and in predementia syndromes
such as mild cognitive impairment (MCI). NPS in MCI confer a greater risk for conversion to …

Objective To examine reciprocal relations of loneliness and cognitive function in older
adults. Methods Data were analyzed from 8382 men and women, age 65 and older …

Background: Mild behavioral impairment (MBI) is a construct that describes the emergence
at≥ 50 years of age of sustained and impactful neuropsychiatric symptoms (NPS), as a …

Objective: Public health campaigns encouraging early help seeking have increased rates of
mild cognitive impairment (MCI) diagnosis in Western countries, but we know little about …

Background Because anxiety is postulated as a risk factor for dementia, we performed a
systematic review and meta-analysis to investigate whether anxiety predicts cognitive …

Objective: To understand the role of depressive symptoms in preclinical Alzheimer's
disease, it is essential to define their temporal relationship to Alzheimer's proteinopathies in …

Introduction Apathy is common in neurocognitive disorders (NCD) but NCD‐specific
diagnostic criteria are needed. Methods The International Society for CNS Clinical Trials …