TCF7L2: the biggest story in diabetes genetics since HLA?

E Zeggini, MI McCarthy - Diabetologia, 2007 - Springer
Much has been made over the past decade of the potential for genetics to advance our
understanding of the pathogenesis of type 2 diabetes and to 'revolutionise'management of …

[图书][B] Wissenschaft in den Medien

MS Schäfer - 2007 - Springer
Diesem Buch liegt eine Dissertation zugrunde, die im Kontext des Forschungsprojektes
„Mediale Diskurse liber Humangenomforschung in Deutschland und den USA im Vergleich" …

Misconceptions about the use of genetic tests in populations

P Vineis, P Schulte, AJ McMichael - The Lancet, 2001 - thelancet.com
Numbers needed to screen To assess the role of a gene-environment interaction and
screening in a population we need to know the penetrance of the genetic trait and its …

Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities

F Becker, CG Van El, D Ibarreta, E Zika… - European journal of …, 2011 - nature.com
Background and purpose During the years prior to the turn of the century, scientific and
medical attention for genetic disorders was mainly focused on understanding rare single …

Human genetic disorders caused by mutations in genes encoding biosynthetic enzymes for sulfated glycosaminoglycans

S Mizumoto, S Ikegawa, K Sugahara - Journal of Biological Chemistry, 2013 - ASBMB
A number of genetic disorders are caused by mutations in the genes encoding
glycosyltransferases and sulfotransferases, enzymes responsible for the synthesis of …

Complex disease and the new clinical sciences

J Rees - Science, 2002 - science.org
Medical research today is dominated by a genocentric point of view. At the same time,
clinical discovery and patient-oriented research have become less common. Here, I suggest …

Moderación en la actividad médica preventiva y curativa. Cuatro ejemplos de necesidad de prevención cuaternaria en España

J Gérvas - Gaceta Sanitaria, 2006 - Elsevier
La actividad clínica tiene más ventajas que inconvenientes, lo que justifica su realización, y
su aprecio social. Sin embargo, con el curso de los años y el desarrollo tecnológico, están …

[图书][B] Breast cancer genes and the gendering of knowledge

S Gibbon - 2006 - Springer
Although the 'inherited susceptibility'genes BRCA 1 and 2 are only thought to be involved in
approximately 5–10 per cent of all cases of breast cancer, risk assessment and genetic …

[图书][B] Die Herstellung einer öffentlichen Hegemonie

J Gerhards, MS Schäfer - 2006 - Springer
Die hier vorgelegte Studie ist aus einem vom Bundesministerium fiir Bildung und Forschung
im Rahmen des Programms „Forschung zu den ethischen, rechtlichen und sozialen Aspekte …

Family history assessment: strategies for prevention of cardiovascular disease

SC Hunt, M Gwinn, TD Adams - American journal of preventive medicine, 2003 - Elsevier
Family history assessment can be used to combine population-wide health promotion and
risk-reduction efforts with a high-risk, targeted approach to help reduce the burden of …