Objective: To identify associations between polymorphisms within the interleukin-1β gene
cluster, all of which increase protein expression, and preeclampsia. Methods: We genotyped …

Attitudes about genetic testing are likely to be an important determinant of uptake of
predictive genetic tests among the general public. Several prior studies have suggested that …

With the official completion of the Human Genome Project in April 2003, we have both the
opportunity and the imperative to translate this unprecedented scientific accomplishment …

Asthma belongs to the category of classical allergic diseases which generally arise due to
IgE mediated hypersensitivity to environmental triggers. Since its prevalence is very high in …

If a transformation in medicine occurs in the wake of the Human Genome Project, its likely
focus will be prevention, a logical extension of the lessons of variation and individuality …

Genetic testing is currently subject to little oversight, despite the significant ethical issues
involved. Repeated recommendations for increased regulation of the genetic testing market …

As patients are increasingly involved in the selection of their care, communication between
health care providers and patients takes on new importance. The present article reviews the …

Evry, France; Durham, NC; Milan, Italy; Oxford, United Kingdom; Leeds, United Kingdom;
and Salt Lake City, Utah code occurs in 1 of every 1000 base pairs; thus a total of 3,000,000 …

Association between hypertension and variation in the α-and β-adducin genes in a white
population. Background The substitution of tryptophan for glycine at amino acid 460 …

The aim of this chapter is to explain and highlight a consistent pattern of changes within
pharmaceutical R&D processes that produce ''small molecule''therapeutics. In doing so, it …