Understanding gut dysbiosis for hepatocellular carcinoma diagnosis and treatment

J Yu, X Chen, X Yang, B Zhang - Trends in Endocrinology & Metabolism, 2024 - cell.com
The gut microbiome can play a crucial role in hepatocellular carcinoma (HCC) progression
through the enterohepatic circulation, primarily acting via metabolic reprogramming and …

Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications, inflammation, and …

KR LeFort, W Rungratanawanich, BJ Song - Cellular and Molecular Life …, 2024 - Springer
This review provides an update on recent findings from basic, translational, and clinical
studies on the molecular mechanisms of mitochondrial dysfunction and apoptosis of …

Ethanol-Producing Enterocloster bolteae Is Enriched in Chronic Hepatitis B-Associated Gut Dysbiosis: A Case–Control Culturomics Study

R Magdy Wasfy, B Mbaye, P Borentain, M Tidjani Alou… - Microorganisms, 2023 - mdpi.com
Background: Hepatitis B virus (HBV) infection is a global health epidemic that causes fatal
complications, leading to liver cirrhosis and hepatocellular carcinoma. The link between …

Beneficial Effects of Synbiotics on the Gut Microbiome in Individuals with Low Fiber Intake: Secondary Analysis of a Double-Blind, Randomized Controlled Trial

A Mantri, L Klümpen, W Seel, P Krawitz, P Stehle… - Nutrients, 2024 - mdpi.com
Insufficient dietary fiber intake can negatively affect the intestinal microbiome and, over time,
may result in gut dysbiosis, thus potentially harming overall health. This randomized …

Association between gut microbiota and seven gastrointestinal diseases: a Mendelian randomized study

SJ Zhu, Z Ding - The Journal of Gene Medicine, 2024 - Wiley Online Library
Background Observational research has shed light on the ability of gut microbes to influence
the onset and progression of gastrointestinal diseases. The causal relationships between …

Impact of the gut microbiome on immunological responses to COVID-19 vaccination in healthy controls and people living with HIV

S Ray, A Narayanan, J Vesterbacka… - npj Biofilms and …, 2023 - nature.com
Abstract Although mRNA SARS-CoV-2 vaccines are generally safe and effective, in certain
immunocompromised individuals they can elicit poor immunogenic responses. Among these …

[HTML][HTML] The role of gut microbiome in hepatocellular carcinoma: A systematic review

Y Trivedi, Z Bolgarina, HN Desai, M Senaratne… - Cureus, 2023 - ncbi.nlm.nih.gov
Gut microbiome dysbiosis is common in patients with chronic liver diseases such as
hepatocellular carcinoma (HCC) and plays an essential role in developing, diagnosing, and …

Establishing and Externally Validating a Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score-Based Nomogram for Predicting Early Recurrence in BCLC …

X Liu, Z Qiu, E Ndhlovu, Y Wan, H Sun… - Journal of …, 2024 - Taylor & Francis
Purpose Early recurrence (ER) is associated with poor prognosis in hepatocellular
carcinoma (HCC). In this study, we developed and externally validated a nomogram based …

[PDF][PDF] 乙型肝炎相关慢性肝病与肠道微生态

徐翔, 秦旨文, 郑齐, 倪佳丽, 罗宝珍, 盛国平 - 中国微生态学杂志, 2024 - cjm.dmu.edu.cn
全球乙型肝炎病毒感染者人数众多, 如未进行及时, 有效的治疗, 慢性乙型肝炎往往会发展为肝
硬化, 肝细胞癌和肝衰竭等. 随着对肠道微生态的逐渐关注和肠− 肝轴概念的提出 …

[PDF][PDF] Gut Dysbiosis Signatures Associated with Hepatitis B Virus-Related Diseases: An Insightful Review Using AI-Powered Research Tools

RM Wasfy, MT Alou, P Borentain, S Ranque, D Raoult… - 2024 - amu.hal.science
Background: Hepatitis B virus (HBV) has threatened public health, mainly resulting in liver
19 fibrosis, cirrhosis, and even damage due to hepatic carcinoma. Growing evidence has 20 …